Maternally inherited familial hypercholesterolemia (FH) impairs glucose metabolism and increases cardiovascular risks in the offspring to a greater degree than paternal inherited FH. However, it remains unknown whether hypertriglyceridemia affects glucose metabolism via inheritance. In this study, we sought to compare the impact of maternally and paternally inherited hypertriglyceridemia on glu...

OBJECTIVE To study the relationship between maternal circulating fuels and neonatal size and compare the relative effects of glucose and lipids. RESEARCH DESIGN AND METHODS The Pune Maternal Nutrition Study (1993-1996) investigated the influence of maternal nutrition on fetal growth. We measured maternal body size and glucose and lipid concentrations during pregnancy and examined their relati...

OBJECTIVE There is strong evidence that low birth weight is associated with glucose intolerance and diabetes in adults. We have carried out a twin study to distinguish among maternal influences, which affect both twins; fetoplacental influences, which are unique to each twin; and the genetic factors that may underlie this association. RESEARCH DESIGN AND METHODS We identified a sample of 423 ...

OBJECTIVE To evaluate the effects of Ramadan fasting on fetal development and outcomes of pregnancy. METHODS We performed this study in Antakya State Hospital of Obstetrics and Child Care, between 28 June 2014 and 27 July 2014 (during the month of Ramadan). A total of two hundred forty healthy pregnant women who were fasting during Ramadan, were included in the groups. The three groups were d...

We formulate quenched chiral perturbation theory for heavy-light mesons coupled to pions, and calculate the one-loop chiral logarithmic corrections to fB, fBs , BB and BBs . We also calculate these corrections for “partially quenched” theories. In both theories, the chiral logarithms diverge in the chiral limit, indicating that (partially) quenched theories should not be used to study this limi...

Aim &Background: Muslims fast from sunrise to sunset during Ramadan, the 9th lunar month. The duration of fasting varies from 13 to 18 hrs per day. Fasting individuals abstain from drinking liquids and eating foods. Manypregnant women and gynecologists are concerned about the possible complicationsassociated with fasting and effects on fetal health. The aim of this study was to determine the ef...

OBJECTIVE The objective of this study was to determine maternal hormonal and metabolic factors associated with insulin sensitivity in human pregnancy. RESEARCH DESIGN AND METHODS This was a prospective observational cross-sectional study of 180 normal pregnant women, using samples collected at the time of a blinded oral glucose tolerance test (OGTT) between 24 and 32 weeks' gestation as an an...

OBJECTIVE The purpose of this article was to examine metabolic risk factors for type 2 diabetes in children and adolescents as a function of maternal versus paternal family history of type 2 diabetes and to examine whether differences in these risk factors emerge during adolescent growth. RESEARCH DESIGN AND METHODS A total of 247 overweight Latino children (baseline age = 11.1 +/- 1.7 years)...

The key findings of this multi-centre prospective cohort study were that neonates born to mothers treated for Gestational diabetes mellitus (GDM) (by lifestyle or medication, e.g. insulin metformin) had high rates macrosomia but similar adiposity those with normal glucose tolerance. In contrast, untreated who overweight and a tolerance increased adiposity. Increased gestational weight gain was ...