Magnesium sulphate is currently the most ideal drug for the treatment of eclampsia but its use in Nigeria is still limited due its cost and clinicians inexperience with the drug. The purpose of this study was to determine whether a shortened postpartum course of magnesium sulphate is as effective as the standard Pritchard regimen in controlling fits in eclampsia Between January and June 2011, 9...

objective: considering the various evidences due to effects of trace elements on the outcome of pregnancy, we decided to assess the effect of these elements levels in maternal and cord serum on low birth weight. materials and methods: an analytical cross-sectional study was performed on 344 pregnant women in labour and their neonates in maryam, akbarabadi and vali-e-asr hospitals in tehran, ir...

Structured abstract Question: In women with pre-eclampsia, does peripartum administration of magnesium sulfate decrease the risk of eclampsia, maternal morbidity, or neonatal morbidity compared to placebo? Design: Multicentre, randomized, double-blind, placebo-controlled trial. Setting: One hundred and seventy-five secondary and tertiary level hospitals in 33 countries. Patients: Ten thousand o...

OBJECTIVES We tested the hypothesis that administration of magnesium sulfate in labor protects against the development of neonatal brain lesions and cerebral palsy (CP) in low birth weight infants. METHODS Magnesium exposure was ascertained in a population-based cohort of 1105 infants weighing 2000 g or less through review of medical records of maternal magnesium sulfate administration and, w...

OBJECTIVE Magnesium sulphate is recommended by international guidelines to prevent eclampsia among women with pre-eclampsia, especially when it is severe, but fewer than 70% of such women receive magnesium sulphate. We aimed to identify variables that prompt Canadian physicians to administer magnesium sulphate to women with pre-eclampsia. METHODS Data were used from the Canadian Perinatal Net...

The aim of this study was to compare the therapeutic efficacy of alginate-based reflux suppressant and magnesium-aluminium antacid gel for treatment of heartburn in pregnancy. A double-blinded, randomized, controlled trial was conducted. One hundred pregnant women at less than 36 weeks gestation with heartburn at least twice per week were randomized to either alginate-based reflux suppressant o...

This study was designed to evaluate the correlation between vitamin and mineral levels of mothers and their neonates. Vitamin, mineral and biochemical parameters were assessed from samples of maternal blood, hair and milk and neonatal hair, umbilical cord blood and meconium. Neonatal retinol plasma levels as well as neonatal alphaand gamma-tocopherol levels were significantly lower (P < 0.01) t...

BACKGROUND Pre-eclampsia is a pregnancy-specific disorder of widespread vascular endothelial dysfunction that occurs after twenty weeks of gestation. OBJECTIVES The aim of the present study was to compare maternal circulating levels of endothelial dysfunction mediators, including the vascular actions of adrenomedullin (AM) and calcitonin gene-related peptide (CGRP), the angiogenic factor of s...

OBJECTIVE Magnesium level is known to decline during pregnancy. A suggested role for magnesium deficiency in conditions like pre-eclampsia and pre-term birth has prompted studies with conflicting evidence. The primary objective of this study was to determine the prevalence of hypomagnesemia in pregnancy, while the secondary objectives attempted to define maternal and fetal outcome due to hypoma...