Numerous large clinical studies have evaluated the evidence regarding magnesium sulfate, neuroprotection, and preterm births. The Committee on Obstetric Practice and the Society for Maternal-Fetal Medicine recognize that none of the individual studies found a benefit with regard to their primary outcome. However, the available evidence suggests that magnesium sulfate given before anticipated ea...

BACKGROUND Epidemiological and basic science evidence suggests that magnesium sulphate before birth may be neuroprotective for the fetus. OBJECTIVES To assess the effectiveness and safety of magnesium sulphate as a neuroprotective agent when given to women considered at risk of preterm birth. SEARCH STRATEGY We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (October ...

BACKGROUND Preferred anticonvulsant used to treat and prevent fits in eclampsia currently is magnesium sulphate. Clinical monitoring of tendon reflexes, respiration rate and measuring hourly urine output should be done to ensures safe administration of magnesium sulphate. OBJECTIVE This study was conducted to evaluate maternal outcomes of magnesium sulphate and diazepam use in the management ...

OBJECTIVE To investigate whether in utero exposure to magnesium sulfate is associated with a lower incidence of cranial ultrasonographic abnormalities that predict cerebral palsy in infants who weigh less than 1501 g at birth. DESIGN For a prospective study of the antecedents of cranial ultrasonographic abnormalities, we enrolled infants who weighed 500 to 1500 g when born at five institution...

We studied the association between the prenatal diets of 212 mothers assessed by a semiquantitative food frequency questionnaire and the blood pressure of their infants. Prenatal potassium, calcium, and magnesium intakes were measured and adjusted for total caloric intake. Infant blood pressure was measured at 2-3 days and at 1, 6, and 12 months of age by using an ultrasonic-auscultatory device...

BACKGROUND Hypertensive disorders of pregnancy result in significant maternal morbidity and mortality. State and national guidelines have been proposed to increase treatment of patients with hypertensive emergencies or critically elevated blood pressures. There are limited data available to assess the impact of these recommendations on maternal morbidity. OBJECTIVE The purpose of this prospec...

OBJECTIVE To study the levels of trace elements zinc (Zn), copper (Cu), magnesium (Mg), calcium (Ca) and phosphorus (P) at term and to assess their correlation in maternal and cord blood. METHODS Fifty two women and their cord blood were studied in a tertiary care hospital in Karachi, Pakistan at the time of delivery. Zn, Cu and Mg were analyzed on atomic absorption spectrophotometer and Ca a...

BACKGROUND Preterm birth is the leading cause of infant mortality globally, including Brazil. We will evaluate whether oral magnesium citrate reduces the risk of placental dysfunction and its negative consequences for both the fetus and mother, which, in turn, should reduce the need for indicated preterm delivery. METHODS/DESIGN We will complete a multicenter, randomized double-blind clinical...

background: preterm labor is the leading cause of infant morbidity and mortality so it may be necessary to administer tocolytics for treatment of it. objective: the aim of this study was to compare the efficacy and safety of magnesium sulfate and nifedipine in the management of preterm labor. materials and methods: 100 women with documented preterm labor were randomly assigned to receive magnes...

The aim of our study was to assess the feasibility of implementing a protocol for the use of magnesium sulfate to prevent cerebral palsy. This retrospective single-center study included all women with fetuses of gestational age <33 weeks of gestation whose birth was planned or expected within 24 hours from September 2011 to December 2012. They were to receive magnesium sulfate, administered int...