Drug discovery projects often involve organizing compounds in the form of a hierarchical tree, where each node is a substructure fragment shared by all of its descendent nodes. A method is described for producing 2D depiction layout coordinates for each of the nodes in such a tree, ensuring that common fragments within molecular structures are drawn in an identical way, and arranged with a cons...

Endoscopic retrograde laser lithotripsy of common bile duct stones is a new technique which can be carried out through the endoscope without anaesthesia using ordinary endoscopic equipment. In the method described here a flashlamp pulsed Neodymium YAG laser (wave length 1064 nm) was used. Light energy was transmitted along a highly flexible quartz fibre with a diameter of 0.2 mm. This new techn...

background: the study evaluated qualitative pcr, primers 121-122 as a tool to follow up evolution parasite load of trypanosoma cruzi . methods: the study was conducted at the state university of maringa, in 2015. step 1, dilutions 1/10 were performed from t. cruzi -y strain to obtain preparations of 50,000-0.05 parasites/ml from which dna were extracted, quantified, and amplified. step 2, the e...

Michael Diaz, Zaria Opara, Heysel Morales, Steven Hawkins, Louise Kelly, Allan Knox PURPOSE: Low-to-moderate intensity aerobic exercise has been reported to elicit changes in systemic hemodynamics. Recent evidence suggests that the cerebral circulation reacts independently circulations same physiological stimuli. The aim of this is determine influence high-intensity on common carotid artery (CC...