In March 1998, the U.S. Environmental Protection Agency (EPA) published a proposal to raise the drinking water maximum contaminant level goal (MCLG) for chloroform, a suspected human carcinogen, from zero to 300 parts per billion. The proposal marked a departure from the agency's traditional reliance on linear dose-response models in performing risk assessment, and reflected the new thinking co...

Modal μ-calculus is an expressive specification formalism for temporal properties of concurrent programs represented as Labeled Transition Systems (Ltss). However, its practical use is hampered by the complexity of the formulas, which makes the specification task difficult and error-prone. In this paper, we propose Mcl (Model Checking Language), an enhancement of modal μ-calculus with high-leve...

A. Saidu, K. A. Dabai, S.A Ogunsina, Y.D. Samsin, S.B. Muhammad Abstract— The conditions to measure the gross beta radioactivity in water samples from the permanent site of Usmanu Danfodiyo University Sokoto in Sokoto State Nigeria were established. The gross beta radioactivity of water samples were measured using proportional gas counter. The result show that the gross beta radioactivity in mo...

background: the electron contamination may reduce or even diminish the skin sparing property of the megavoltage beam. the detailed characteristics of contaminant electrons are presented for different field sizes and cases. materials and methods: the monte carlo code, mcnpx, has been used to simulate 18 mv photon beam from a varian linac-2300 accelerator. all dose measurements were carried out u...

FTY720, Fingolimod, is a functional antagonist to the sphingosine-1-phosphate (S1P) receptor and an inhibitor of sphingosine kinase 1. Here, we showed that a combination of FTY720 and TRAIL induced apoptosis in human renal, breast, and colon carcinoma cells. Most importantly, this combination had no effect on normal cells. Furthermore, the combined treatment with FTY720 and TRAIL reduced tumor ...

Abstract In recent years, more intensive chemotherapy regimens for mantle cell lymphoma (MCL) have been associated with prolongation of survival. In this study, our aim was to investigate prognostic factors and evaluate improvement in survival in MCL on a population level. The cohort included all patients diagnosed with MCL from 1 January 2000 to 31 March 2010 in the Swedish Lymphoma Registry...

Mutations have been described in the ataxia telangiectasia mutated (ATM) gene in small numbers of cases of lymphoid neoplasia. However, surveys of the ATM mutation status in lymphoma have been limited due to the large size (62 exons) and complex mutational spectrum of this gene. We have used microarray-based assays with 250,000 oligonucleotides to screen lymphomas from 120 patients for all poss...

Anterior cruciate ligament (ACL)-derived cells have a character different from medial collateral ligament (MCL)-derived cells. However, the critical difference between ACL and MCL is still unclear in their healing potential and cellular response. The objective of this study was to investigate the mesenchymal differentiation property of each ligament-derived cell. Both ligament-derived cells dif...

The purpose of this work is to propose a new methodology to ameliorate the Markov Cluster (MCL) Algorithm that is well known as an efficient way of graph clustering (Van Dongen, 2000). The MCL when applied to a graph of word associations has the effect of producing concept areas in which words are grouped into the similar topics or similar meanings as paradigms. However, since a word is determi...