Male breast cancer (MBC) is a rare and poorly studied disease that is a growing global health problem. Interestingly, both the molecular basis of MBC and its histological profile are often quite distinct from the far more prevalent female breast cancer, emphasizing the need for increased focus on MBC. Here, we present a case report of an MBC patient from India with a strong familial history of ...

Mature microRNAs (miRNAs) are small non-protein coding RNAs that modulate gene expression after transcription. Few studies have shown that male breast cancer (MBC) shows distinctive miRNAs pattern, suggesting its relevance in this pathology. To study this, we performed a profile of 800 miRNAs in 9 MBC samples and in normal epithelial cells of 3 MBC cases. EXPERIMENTAL DESIGN Of FFPE tissues, ...

Male breast cancer (MBC) is rare, with the peak age of onset at 71 years. BRCA2 mutations are more frequent than BRCA1 with 20% of cases giving a family history. Risk factors for MBC are poorly understood and include working in high-ambient temperatures and exhaust fume exposure. MBC is associated with hyperoestrogenic states found in liver disease, Klinefelter's syndrome, gonadal dysfunction o...

The aim of this study is to determine the sensitivity of polyphenol green tea on mutans streptococci. Tea is a traditional drink that is beneficial to health. One of its benefits is its capability to prevent dental caries because it has active substance polyphenol.An extract of green tea non-fermented tea leaves of Camellia sinensis and its chromatographically isolated polyphenol compound was e...

OBJECTIVE Mucinous breast carcinoma (MBC) is classified into mixed mucinous breast carcinoma (MMBC) and pure mucinous breast carcinoma (PMBC) based on whether the tumor is with or without a component of invasive ductal carcinoma, respectively. PMBC is subtyped into hypocellular PMBC (PMBC-A) and hypercellular PMBC (PMBC-B). METHODS Of 1,760 primary breast carcinomas, 71 were diagnosed as MBC,...

The Mapping Based Constraint handling (MBC) method for evolutionary search methods was suggested and proved to be a new promising constraint handling method, 6]. The MBC method is based on an assumption that a bounded feasible solution domain can be mapped into a simple hypercubic domain. The result of applying MBC is to create a new unconstrained optimisation problem out of the originally cons...

It is a long-standing challenge to combine mixed monomers into multiblock copolymer (MBC) in a onepot/one-step polymerization manner. We report the first example of MBC with biodegradable polycarbonate and polyester blocks that were synthesized from highly efficient one-pot/one-step polymerization of cyclohexene oxide (CHO), CO2 and 3-caprolactone (3-CL) in the presence of zinc– cobalt double m...

Purpose: The utility of circulating tumour cells (CTCs) as a prognostic marker in metastatic breast cancer (MBC) has been well-established. However, their efficacy and accuracy are still under scrutiny mainly due to methods of their enrichment and identification. We hypothesized that circulating microRNAs (miRNAs) can predict the CTC status of MBC patients, and tested for the same. Furthermore,...

PURPOSE To investigate clinicopathological characteristics and outcomes of male breast cancer (MBC). PATIENTS AND METHODS We retrospectively analyzed the data of 20 MBC patients in comparison with female ductal carcinoma treated at Yonsei University Severance Hospital from July 1985 to May 2007. Clinicopathological features, treatment patterns, and survival were investigated. RESULTS MBC co...

BACKGROUND Treatment options for patients with metastatic breast cancer (MBC) include a rapidly expanding repertoire of medical, surgical and supportive care measures. DESIGN To provide timely and evidence-based recommendations for the diagnostic workup and treatment of patients with MBC, an international expert panel reviewed and discussed the evidence available from clinical trials regardin...