The inference of gene regulatory networks is a core problem in systems biology. Many inference algorithms have been proposed and all suffer from false positives. In this paper, we use the minimum description length (MDL) principle to reduce the rate of false positives for best-fit algorithms. The performance of these algorithms is evaluated via two metrics: the normalized-edge Hamming distance ...

This document has been prepared at the request of the Secretariat of the FAO Commission on Genetic Resources for Food and Agriculture, and in close collaboration with the FAO Plant Production and Protection Division, to facilitate the Commission’s deliberations when it will review key issues on targets and indicators for plant genetic resources for food and agriculture at its Fifteenth Regular ...

Introduction: The selection of suitable beam angles and weights in external-beam radiotherapy is at present generally based upon the experience of the planner. Therefore, automated selection of beam angles and weights in forward-planned radiotherapy will be beneficial. Material and Methods: In this work, an efficient method is presented within the MATLAB environment to investigate how to improv...

The Rissanen (MDL) and Wallace (MML) formulations of learning by compact encoding only provide a decision criterion to choose between two or more models, they do not provide any guidance on how to search through the model space. Typically, deterministic search techniques such as the expectation maximization (EM) algorithm have been used extensively with the MML/MDL principles to find the single...

In this paper we propose a new criterion, based on Minimum Description Length (MDL), to estimate an optimal number of clusters. This criterion, called Kernel MDL (KMDL), is particularly adapted to the use of kernel K-means clustering algorithm. Its formulation is based on the definition of MDL derived for Gaussian Mixture Model (GMM). We demonstrate the efficiency of our approach on both synthe...

For the evolutionary algorithm, the representation of the electronic circuit has two methods, one kind is code with the electronic circuit solution space, the other is code with the problem space. How one representation quality weighs may think the following questions? The first is the code method should as far as possible complete, it is say for the significance solution circuit or the optimiz...

Meiosis is the specialized cell division that gives rise to gametes (reproductive cells such as sperm or eggs, or spores in yeast). To complete meiosis, a cell duplicates its chromosomes once but then goes through two rounds of chromosome segregation, reducing the genome by half. The original chromosome number is restored by the fusion of gametes during fertilization to form a zygote. Meiosis i...

With the explosive growth of wireless communication system and portable devices, the power reduction has become a major problem. Many of the communication system today utilize digital signal processors (DSP) to resolve the transmitted information. Finite impulse response (FIR) filters have been and continued to be important building blocks in many digital processing systems (DSP). Hamming dista...

The capacity of mode-division multiplexing (MDM) systems is limited, for a given outage probability, by mode-dependent loss (MDL) and gain. Modal degrees of freedom may be exploited to increase transmission rate (multiplexing gain) or lower outage probability (diversity gain), but there is a fundamental tradeoff between the achievable multiplexing and diversity gains. In this Letter, we present...