With the rapidly expanding use of fluorescent lamps (FLs) and increasing interest in conservation and sustainable utilization of critical metals such as rare earth elements (REEs), the recovering of REEs from phosphors in waste FLs is becoming a critical environmental and economic issue. To effectively recycle REEs with metallurgical methods, mechanical activation by ball milling was introduced...

Intracellular and extracellular mechanical environments have a significant impact on survival and proliferation of cells. While the extracellular signal-regulated kinase (ERK) subfamily of MAP kinases plays critical roles in regulations of these cellular behaviors, activation of ERK is affected by mechanical conditions of cells. We have recently found that ERK is activated on contractile actomy...

abstract background : today, as many as 1.5 million americans use ventilators once in a year. .response to mechanical ventilation alarms remains to be one of the most challenging tasks facing physicians, nurses or other medical personnel in the icu. in the present study we aimed to compare the response times to “vocal alarms” and “visual or audible ones”. methods : in the present study we devel...

The hypothesis that the pattern of muscle activation during a static voluntary effort exerted in different directions is oriented in the direction of the muscle's mechanical action was evaluated. The electromyographical (EMG) activation patterns of five hip muscles (gluteus medius, rectus femoris, tensor fasciae latae, gracilis and semitendinosus) and one knee muscle (vastus lateralis) were cha...

OBJECTIVE AND METHODS We have previously demonstrated that mechanical loading of cardiac fibroblasts leads to increased synthesis and gene expression of the extracellular matrix protein collagen. We hypothesised that the upregulation of procollagen gene expression in cardiac fibroblasts, in response to cyclic mechanical load, is mediated by one or more members of the MAP kinase family. To test ...

Mechanical forces affect all the tissues of our bodies. Experiments conducted mainly on cultured cells have established that altering these forces influences cell behaviors, including migration, differentiation, apoptosis, and proliferation [1, 2]. The transcriptional coactivator YAP has been identified as a nuclear relay of mechanical signals, but the molecular mechanisms that lead to YAP acti...

Mechanical forces exerted on cells impose stress on the plasma membrane. Cells sense this stress and elicit a mechanoelectric transduction cascade that initiates compensatory mechanisms. Mechanosensitive ion channels in the plasma membrane are responsible for transducing the mechanical signals to electrical signals. However, the mechanisms underlying channel activation in response to mechanical...

Spinal activation of the cAMP pathway produces mechanical hyperalgesia, sensitizes nociceptive spinal neurons, and phosphorylates the transcription factor cAMP-responsive element binding protein (CREB), which initiates gene transcription. This study examined the role of the cAMP pathway in a model of chronic muscle pain by assessing associated behavioral changes and phosphorylation of CREB. Bil...

Reduced the temperature for the LiNH2 to Li2NH transition from 120C to 50C via mechanical activation. This reduction paves the way for near-room-temperature hydrogen sorption and desorption of the LiNH2 + LiH system. Enhanced hydrogen sorption and desorption rates of the LiNH2 + LiH system at and below 200 C via mechanical activation. Identified the dehydriding behavior and issues associated wi...