Although MEMS gyroscopes are simpler to integrate into electronic systems than their mechanical predecessors, many factors still require consideration, including trade-offs among function, performance, and price. For many systems, a key performance metric is accuracy. Although off-the-shelf products may satisfy some design requirements, a gyroscope that appears to suit a system design may end u...

During the design process, a designer transforms an abstract functional description for a device into a physical description that satisfies the functional requirements. In this sense, design is a transformation from the functional domain to the physical domain; however, this transformation process is not well characterized nor understood for mechanical systems. The difficulty arises, at least i...

Guided self-organization can be regarded as a paradigm proposed to understand how to guide a self-organizing system towards desirable behaviors, while maintaining its non-deterministic dynamics with emergent features. It is, however, not a trivial problem to guide the self-organizing behavior of physically embodied systems like robots, as the behavioral dynamics are results of interactions amon...

Although pathological changes in axonal morphology have emerged as important features of traumatic brain injury (TBI), the mechanical vulnerability of the axonal microcompartment relative to the cell body is not well understood. We hypothesized that soma and neurite microcompartments exhibit distinct mechanical behaviors, rendering axons more sensitive to a mechanical injury. In order to test t...

aluminum alloys such as al 5083 have primary potential for lightweight structural application in automotive and aerospace industries. this paper addresses the mechanical and tribological properties and corrosion resistance of chromium nitride coatings deposited on al 5083 that can be used for development of applications of aluminum 5083 alloy. the crn coatings of 1 μm thickness were deposited b...

Langmuir monolayers of long-chain fatty acids display a wide range of interesting flow and phase behaviors, but the correlation between these behaviors varies. In this paper, we report two interesting behaviors in a Langmuir monolayer of 2-hydroxy-tetracosanoic acid: phase coexistence between the L(2h) and L(2)' phases over a large pressure range and a peak in the viscosity and elastic modulus ...

BACKGROUND Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors are present in the spinal dorsal horn and dorsal root ganglia, suggesting an important role of PACAP-PACAP receptors signaling system in the modulation of spinal nociceptive transmission. We have previously reported that a single intrathecal injection of PACAP or a PACAP specific (PAC1) receptor selective ag...

BACKGROUND Physicians have long reported that patients with chronic pain show higher tendencies for alcohol use disorder (AUD), and AUD patients appear to have higher pain sensitivities. The goal of this study was to test 2 hypotheses: (i) binge alcohol consumption increases inflammatory pain and mechanical and cold sensitivities; and (ii) tigecycline is an effective treatment for alcohol-media...