introduction: radiation induced bystander effect (ribe) which cause radiation effects in non-irradiated cells, has challenged the principle according to which radiation traversal through the nucleus of a cell is necessary for producing biological responses. what is the mechanism of this phenomenon? to have a better understanding of this rather ambiguous concept substantial number of original an...

cancer is one of the most fatal diseases in human beings which annually leads to death of 30000 individuals in iran. prevention, diagnosis and treatment of cancer is one of the major scientific challenges all around the world. it seems that increased incidence of several cancers such as colon and prostate and their mortality are connected with obesity. it is suggested that obesity and metabolic...

the oxidation of n-pentanol by tetramethylammonium fluorochromate in acidic solution wasstudied using spectrophotometric technique. the reaction was arranged to be under pseudo firstorderconditions respect to the oxidant. a michaelis-menten type kinetic was observed respect tothe substrate. the reaction is catalyzed by hydrogen ions. dependences of the reaction rates ontemperature and different...

the aim of this study was to compare defense styles and mechanisms in adult patients suffering from obsessive-compulsive disorder (ocd), and panic disorder (pd) with normal subjects in iran.defensive patterns of 22 patients with ocd, 28 patients with pd and those of 116 normal individuals (as a control group) were assessed using the farsi version of defense style questionnaire-40 (dsq-40). the ...

oxidative stress has been implicated in the progression of hiv to aids, since hiv usually replicates in a highly oxidized condition and cd4+ t lymphocytes can be activated via a cascade of internal oxidative pathways, which enhances the formation of proteins and enzymes. thus, antioxidants should potentially be useful for the treatment and prevention of hiv infection as a new alternative strate...

previous, intravenous immunoglobulin (ivig) has been used for treatment of patients with immunodeficiency. however, recent studies have shown that ivig is a suitable approach for treatment of inflammatory and autoimmune diseases. although the exact mechanism of ivig action is not well known, recent findings have demonstrated that ivig impacts on expression and function of fc receptors of immuno...

acrylamide (aa) is an important industrial chemical agent that is mainly used in the production of polymers and copolymers. recently it has been attention because of its production in the diet at high-temperature (>120 ºc) processes such as cooking, frying, toasting, roasting or baking of high carbohydrate foods. according to high exposure to acrylamide, recognition of its toxic effect is neces...

by discovering how chemical compounds/xenobiotics cytotoxicity is affected when their metabolic pathways are inhibited or activated, the metabolic pathways that activate versus detoxify chemical compound can be identified. reactive metabolites contributing to cytotoxicity can also be identified. in this lecture, the pretreatment of inhibitors and activators of xenobiotic metabolizing enzymes as...

By discovering how chemical compounds/xenobiotics cytotoxicity is affected when their metabolic pathways are inhibited or activated, the metabolic pathways that activate versus detoxify chemical compound can be identified. Reactive metabolites contributing to cytotoxicity can also be identified. In this lecture, the pretreatment of inhibitors and activators of xenobiotic metabolizing enzymes as...