The mediation analysis methodology of the cause-and-effect relationship through mediators has been increasingly popular over past decades. human microbiome can contribute to pathogenesis many complex diseases by mediating disease-leading causal pathways. However, standard is not adequate for data due excessive number zero values and over-dispersion in sequencing reads, which arise both biologic...

introduction: this study aims to explain the depression level based on life style through the mediation of social health and quality of life. statistical population was all persons over 18 years of ahwaz random sampling stage sample size were selected 383 people. method: research data in this study were collected by using a health promoting lifestyle questionnaire walker and plyrky, keynesian p...

OBJECTIVE We hypothesize that the effect of aging on memory is mediated by executive function. METHODS Two hundred and thirty healthy adults (101 male, 129 female) were recruited for the study. We used a promising, newly developed, computerized neuropsychological test for the measurement of executive function and memory. The data were analyzed using structural equation modeling and path analy...

Theory and research suggest that people can increase their happiness through simple intentional positive activities, such as expressing gratitude or practicing kindness. Investigators have recently begun to study the optimal conditions under which positive activities increase happiness and the mechanisms by which these effects work. According to our positive-activity model, features of positive...

Family mediation dovetails with family therapy approaches, in particular the brief, solution-based family therapies, such that these two intervention approaches may be considered quite similar. Is it OK for mediators to employ therapeutic methods and methodologies? Is this still mediation or something else? This article explores these issues, examining and comparing mediation and therapy approa...

Karoly Varga is Senior Research Fellow at the Sociological Research Institute of the Hungarian Academy of Sciences. He was recently involved in an evaluation of achievement motivation training programmes in several countries on behalf of UNI DO. Since the first experiment in India by McCelland and Winter (1969), work on achievement motivation development has been attempted in various cultures, ...

BACKGROUND The relative role of socioeconomic status (SES), home environment and maternal intelligence, as factors affecting child cognitive development in early childhood is still unclear. The aim of this study is to analyze the association of SES, home environment and maternal IQ with child neurodevelopment at 18 months. METHODS The data were collected prospectively in the PHIME study, a ne...