Ocular melanoma (OM) is a rare noncutaneous malignancy and consists of 2 different subtypes based on the anatomic location in eye: uveal conjunctival melanoma. Like cutaneous melanoma, OM benefits from nuclear medicine molecular imaging nodal staging clinical management. Through illustration distinctive cases, we aim to demonstrate complementary roles standard lymphoscintigraphy, advanced SPECT...

COVID-19 pandemija sutrikdė ir apribojo visą sveikatos priežiūrą, ypač planinę, tarp jos onkologinę pagalbą, o kartu pagalbą sergantiems melanoma. Darbo tikslas – ištirti palyginti pacientų, sergančių melanoma, stacionarinės medicinos pagalbos prieina­mumą iki pandemijos (2019) (2020) metais. Analizuotos įvairių šalių autorių mokslinės publikacijos nagrinėjama tema, tirtos melanoma sirgusių pac...

Early detection of melanoma is a vital determinant in achieving favorable prognosis and patient outcomes which led to innovations skin imaging modalities that improved the diagnostic accuracy early melanoma. Studies reported cancer its stages using dermoscopy reflectance confocal microscopy, however there are limited reports detecting micro-melanomas less than 2-mm diameter. Previously, smalles...

Background: Although cyclin-dependent kinase 2 (CDK2) is known to be upregulated in certain cancers, its spatial expression pattern melanocytic tumors has remained unknown. Objective: To characterize CDK2 benign and malignant proliferations. Methods: We performed immunohistochemistry (IHC) on normal skin a tumor panel comprising over 200 congenital nevi, dysplastic melanomas situ, invasive mela...

purpose: to report the clinical and histopathological features of recurrent atypical fibrous histiocytoma of the corneo-scleral limbus followed by intra-epithelial squamous neoplasia. case report: a 25-year-old female patient presented with a recurrent vascularized gelatinous mass in the left nasal limbus. the preliminary histopathological diagnosis of the previously excised lesion was an amela...

Melanoma is one of the most aggressive forms cancer, which can be treated only with early detection disease. The article discusses existing algorithms and methods visual diagnosis melanoma. systems automatic dermatoscopic images used by them are also considered. considers limitations hindering development systems: lack relevant domestic data sets that allow training artificial intelligence mode...

Background: Melanoma is a common and malignant cutaneous tumor, which is responsible for a large proportion of skin cancer deaths. Dendritic cell (DC)-based vaccines have achieved positive results in the treatment of melanoma because of their ability to induce cytotoxic response to facilitate tumor elimination. Objective: To improve the efficacy of dendritic ce...

Cemiplimab is the first PD-1 inhibitor approved in United States for treatment of metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) and basal (BCC), but not melanoma. We describe a case amelanotic melanoma (AM) developing patient on cemiplimab therapy invasive SCC. Cutaneous AM rare subtype that shows little no melanin pigmentation clinical histological examination thus oft...