AMA Laliscia C, Genovesi-Ebert F, Perrone et al. Photon-based high-dose single-fraction radiosurgery, an effective treatment modality for recurrent uveal melanoma. Contemporary Oncology/Współczesna Onkologia. 2023. doi:10.5114/wo.2023.129410. APA Laliscia, C., Genovesi-Ebert, F., Perrone, Fuentes, T., Cresti, & Guido, F. (2023). https://doi.org/10.5114/wo.2023.129410 Chicago Concetta, Federica ...

Introduction: The small intestine is the most frequent site of metastatic melanoma. However, its diagnosis continues to be a challenge since it usually asymptomatic or with non-specific symptoms.Few cases result in complications, peritonitis due perforation being infrequent. objective work report clinical case melanoma metastasis intestine. Clinical case: A 66-year-old male patient diagnosed ne...

Skin cancers are one of the most common types cancer in United States [1], and melanoma has steadily increased over last 20 years. Solar ultraviolet radiation (UVR) is known as main cause damaging effects to skin [2], yet also preventable risk factor. Outdoor physical activity, an important health behavior, exposes body UVR thus ostensibly linked increases sunburn, melanoma, non-melanoma [3], [...

Case Description- A 2-yr-old intact male donkey (Equus asinus) was presented to Hospital of Veterinary Medicine, Mansoura University with subcutaneous masses under the tail. Clinical Findings- Physical examination revealed the presence of 2 separate 5x10 and 5x8-cm-diameter, round and firm subcutaneous masses. Treatment and Outcome<...

Malignant melanoma currently accounts for approximately 1%, of all cancer deaths. The incidence of cutaneous melanoma is rising worldwide. The treatment of early-stage melanoma consists primarily of surgical removal of the tumour. The overall 5-years survival rate for malignant melanoma is 81%. Recently, many efforts have been made to analyse the potential significance and the possible relation...

Approximately 10% of melanoma cases report a relative affected with melanoma, and a positive family history is associated with an increased risk of developing melanoma. Although the majority of genetic alterations associated with melanoma development are somatic, the underlying presence of heritable melanoma risk genes is an important component of disease occurrence. Susceptibility for some fam...

Hematogenous dissemination of melanoma is a life-threatening complication of this malignant tumor. Here, we identified junctional adhesion molecule-C (JAM-C) as a novel player in melanoma metastasis to the lung. JAM-C expression was identified in human and murine melanoma cell lines, in human malignant melanoma, as well as in metastatic melanoma including melanoma lung metastasis. JAM-C express...

Hematogenous dissemination of melanoma is a life-threatening complication of this malignant tumor. Here, we identified junctional adhesion molecule-C (JAM-C) as a novel player in melanoma metastasis to the lung. JAM-C expression was identified in human and murine melanoma cell lines, in human malignant melanoma, as well as in metastatic melanoma including melanoma lung metastasis. JAM-C express...

Recent advancement in the research of malignant melanoma is reviewed. Among many gene alterations detected in human melanoma, defect of CDKN2A located at chromosome 9p21 seems to be most important in the earlier developmental phase, though significance of this gene in the evolution of melanoma in situ has not been confirmed yet. Deletions of PTEN/MMAC1 on 10q23.3 and AIM1 on 6q21 as well as mut...

BACKGROUND Melanoma inhibitory activity is a protein secreted by melanoma cells and has been used as a tumor marker. Increased Melanoma inhibitory activity serum levels are related to metastatic disease or tumor recurrence. Currently there are no studies on Melanoma inhibitory activity and cutaneous melanoma involving Brazilian patients. OBJECTIVE To evaluate the performance and feasibility o...