Based on epidemiological data we can assume that at least some malignant melanoma (MM) and breast cancer cases can be caused by the same genetic factors. CDKN2A, which encodes the p16 protein, a cyclin-dependent kinase inhibitor suppressing cell proliferation, is regarded as a major melanoma susceptibility gene and the literature has also implicated this gene in predisposition to breast cancer....

Immunotherapy, in the context of cancers, involves use various drugs to stimulate immune system target cancer cells. Immunotherapy is being increasingly used for cutaneous malignancies, especially melanoma. Immunity plays an important part protection against cancer. One factors limiting effectiveness host immunity improper recognition Sometimes, despite recognizing cells as abnormal, response, ...

Skin cancers are one of the most common types cancer in United States [1], and melanoma has steadily increased over last 20 years. Solar ultraviolet radiation (UVR) is known as main cause damaging effects to skin [2], yet also preventable risk factor. Outdoor physical activity, an important health behavior, exposes body UVR thus ostensibly linked increases sunburn, melanoma, non-melanoma [3], [...

Skin cancer is one of the most common cancers. Melanoma accounts for less than 2% of skin cancer cases but causes a large majority of skin cancer deaths. Early detection of malignant melanoma remains the key factor in saving lives. However, the melanoma diagnosis is still clinically challenging. Here, we developed a confocal photothermal microscope for noninvasive, label-free, three-dimensional...

Skin cancer is the most common form of affecting humans. Melanoma dangerous type skin cancer; and early diagnosis extremely vital in curing disease. So far, human knowledge this field very limited, thus, developing a mechanism capable identifying disease on can save lives, reduce intervention cut unnecessary costs. In paper, researchers developed new learning technique to classify lesions, with...

Melanoma is the deadliest form of skin cancer and responsible for 4% of all cancer deaths and 86% of skin cancer-related deaths in the United States (Losina et al., 2007). Melanoma is caused by malignant growth of the melanocytes, which are melanin-producing cells found in the skin’s epidermis, hair, and eyes. In melanoma, these cells undergo an uncontrollable cell growth that manifests in the ...

The association between rosacea and skin cancer remains inconclusive with conflicting reports. In this nationwide population-based retrospective cohort study we aimed to determine the risk of in patients rosacea. A (n = 11,420) was formulated evaluated from 2010 2019. incidence rate ratios actinic keratosis, (malignant melanoma[MM] non-melanoma cancer[NMSC]), gastric, colorectal, liver were ana...

BACKGROUND Skin cancer is the most common form of cancer in the United States. Melanoma skin cancer is particularly deadly; more than 8000 US residents die from it each year. Although recent reports suggest that melanoma incidence rates have been increasing, these apparent increases could be caused by an increase in reporting and/or screening, and by an actual increase in the occurrence of mela...

Design, synthesis, anticancer, docking, and in silico assessment for 8-piperazinyl caffeinyl-triazolylmethyl hybrid conjugates are explained. These compounds have satisfactory activities against melanoma breast cancer cell lines.

Cancer of the skin is the most common form of malignancy in humans and is divided into two categories – non-malignant skin cancer and cutaneous melanoma. Non-melanoma skin cancer (basal cell and small cell carcinoma) make up a vast majority of skin cancers. According to data from National Cancer Institute (NCI) in 2012, more than 2 million new cases of non-melanomas will be identified with less...