Central nervous system (CNS) infection is associated with high rates of morbidity and mortality, despite advancements in molecular testing, aseptic meningitis remains challenging to diagnose. Aseptic cases are often underreported worldwide, which impacts the quality patient care. Therefore, we aimed assess results BioFire® FilmArray® meningitis/encephalitis (ME) PCR panel, clinical characterist...

conclusions chronic meningitis in immunocompromised hosts can be due to more than one pathologic etiology and we should do all diagnostic evaluation to rule out all possible differential diagnosis. introduction cryptococcal meningitis is a rare disorder that is caused by cryptococcus neoformans in immunocompromised host. case presentation the case was a 64-year-old man with a history of stem ce...

objective bacterial meningitis is still a life threatening epidemiological problem especially in many developing countries; considering its dire consequences, its prompt and accurate diagnosis has become a priority for clinicians. because of the various limitations of conventionally used laboratory techniques, we evaluated and compared the diagnostic utility of c-reactive protein(crp) and lacta...

meningitis, pneumonia, and sepsis in newborns and young infants (age < 60 days) are the main causes of childhood mortality in developing countries. even though streptococcus pneumonia is the most commonly detected microorganism in pediatric bacterial meningitis, it is rare in newborn infants. the following article reports a case of pneumococcal meningitis that was detected early in a newborn in...

conclusions clinicians should be aware that tbm might have unusual presentations. early diagnosis and treatment are essential to decrease mortality and morbidity such as irreversible neurological deficits. case presentation a 66-year-old diabetic man was admitted to our hospital. he complained of prolonged left otalgia and headache. antibiotic therapy was started for mastoiditis and otitis medi...

bacterial infection of the brain is relatively rare in dogs and cats. a cat at approximately three months of age was admitted to the clinic with a history of dog bite seven days before admission. on clinical presentation, the cat was unconscious and in lateral recumbency. one hour after admission, the cat developed severe apnoea and asystole. cardiorespiratory resuscitation was unsuccessful and...

The value of C reactive protein measurement in the differential diagnosis of meningitis was assessed in a population where tuberculous meningitis is prevalent. C reactive protein was measured serially with a sensitive radioimmunoassay in sera from 31 children with bacterial meningitis, 15 with tuberculous meningitis (6 with miliary tuberculosis), and 28 with viral meningitis. Concentrations of ...

It was shown in children that serum procalcitonin was the best marker to use to differentiate bacterial from viral meningitis. To evaluate procalcitonin in the diagnosis of acute bacterial and viral meningitis, we conducted a prospective study including adult patients who were suspected of having meningitis and who were admitted to an emergency department. Cerebrospinal fluid (CSF) and serum le...

To develop such a system, a retrospective study was performed on patients with meningitis admitted at three major pediatric hospitals during a ten-year period. In this study, important cerebrospinal fluid ( CSF) indices were measured and compared in cases of bacterial and viral meningitis. Glucose, protein and white blood cells (WBCs) were analyzed in 609 patients with meningitis and scores wer...

in this study demographic, clinical, paraclinical, microbiological, and therapeutic features of patients with community-acquired acute bacterial meningitis admitted to a referral center for infectious diseases in iran, have been evaluated. medical records of adult (> 18 years) individuals with confirmed diagnosis of community-acquired bacterial meningitis during a 4-year period were retrospecti...