background: different viewpoints exist about lipid screening in all children or only in children with positive family history (fh)of premature cardiovascular diseases (cvds) or hypercholesterolemia. this systematic review and meta-analysis aim to assess the effectiveness of lipid screening in children and adolescents according to the existence of positive fh of cvd risk factors.materials and me...

results we included 20 articles in our meta-analysis. the pooled hbsag prevalence in children of e and m countries was 2.73% (95% ci: %1.73% - 3.72%). the prevalence rates in the emro and middle eastern countries were 1.85% (95% ci: 1.27% - 2.43%) and 2.66% (95% ci: 1.31% - 4.01%), respectively. the prevalence rates amongst children in nations considered in more than one study were 0.81% (95% c...

search results show that numerous primary studies have been carried out in different parts of iran regarding prevalence of g6pd deficiency; if results of these studies are combined, a reliable estimation of prevalence of this factor will be achieved in iran. thus, present study, aimed to determine the prevalence of g6pd deficiency by combining findings of qualified primary studies using meta-an...

abstract: in contrast to traditional reviews, systematic reviews explore theliterature on a specific topic comprehensively using a well-defined protocol and recruit the findings of eligible studies after the assessment of their qualities, using a clear and reproducible method. checking the assumptions, we may merge the findings of recruited studies in a systematic review and use metaanalysis te...

background: a high prevalence of human t-cell lymphotropic virus type 1 (htlv-1) infection among general population in the northeast of iran has been reported. multi-transfused patients are known as ‘at-risk’ group for the infection. this systematic review and meta-analysis was conducted to estimate the prevalence of htlv-1 infection among iranian multi-transfused patients. materials and method...

 abstract the present study aimed to determine the prevalence of hypothyroidism, hypoparathyroidism and the frequency of regular chelation therapy in patients with thalassemia major in iran. searching process was performed by two independent  researchers using valid keywords in the national and international database, including: magiran, iranmedex, sid, medlib, scopus, pubmed, science direct, ...

matrix metalloproteinases (mmps) play an important role in gastric cancer (gc). accumulated evidence suggests that functional mmp-1 and mmp-7 gene polymorphisms are associated with several tumors. the aim of this study was to investigate two single nucleotide polymorphisms, mmp-1 -1607 1g/2g and mmp-7 -181 a/g, and their potential relationship with gc. we examined 246 gc  patients and 252 age-a...

background: coffee is implicated in the susceptibility to several cancers. however, the association between coffee and lymphoma remains unclear. this meta-analysis aimed to assess quantitatively the association between coffee and the incidence of lymphoma. methods: a literature search was performed for cohort and case-control studies published using pubmed, cochrane, and embase databases. studi...

the association between β2-adrenergic receptor (adrb2) -16arg/gly polymorphism (rs1042713) and chronic obstructive pulmonary disease (copd) risk has been investigated in many published studies. however, the results were inconclusive. a meta-analysis was performed to make a more precise estimation of the relationship.the pubmed, embase, isi web of science, the cochrane database of systematic rev...