The effects of methanolic and aqueous extracts of Tribulus terrestris on rat blood pressure (BP) and the perfused mesenteric vascular bed were investigated. The extracts dose-dependently reduced BP in spontaneously hypertensive rats (SHRs) with the aqueous fraction being more potent than the methanolic fraction at all doses tested. In vitro, the methanolic but not aqueous extract produced a dos...

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The study was aimed to evaluate the antioxidant activity of Cassytha filliformis for the first time. The antioxidant activity of cassytha filiformis extracts in hexane, ethyl acetate and methanol were assessed based on their radical scavenging activity (RSA) using the DPPH assay. Methanolic extract showed good antioxidant activity when compared with standard Butylated hydroytoluene(BHT). Furthe...

BACKGROUND A substantial number of the world population especially that of the developing countries rely on herbal products to control their fertility since ancient times. Rumex steudelii Hochst is one of the traditionally used antifertility plants in Ethiopia. Previous studies showed that the methanolic root extract of the plant had reversible antifertility effect in experimental animals. Howe...

The aim of this study was to evaluate extracts from two medicinal plants, Acanthospermum hispidum and Ficus thonningii, used in traditional medicine in Congo Brazzaville, for in vitro antiplasmodial activities against two laboratory strains of Plasmodium falciparum: the chloroquine sensitive 3D7 and the chloroquine resistant Dd2. ELISA HRP2 assay was used to evaluate the in vitro inhibitory act...

Cancer is a disease in which there is an uncontrolled multiplication and spread, within the body, of abnormal forms of the body’s own cells. Assessment of In-vitro cytotoxicity has been recently become popular as a primary screening method for evaluating anticancer activities of various natural source. This study was carried out to characterize anti-cancer activity of methanolic extract of Mich...

Rheumatoid arthritis is a systemic disorder which involves the activation of immune system against the self-tissues. The main targets of this disease are the joints. Being systemic the development of this disease involves different mechanisms and thus the exact cause of this disease remains unknown. Although different drugs have been developed, none has been found to be the cure for this diseas...

Objective: To evaluate antihyperlipidaemic activity of methanolic extract of seeds of Cuminum cyminum L. in hyperlipidaemia in rabbits. Methods: This study was conducted in Pharmacology Department of University of Karachi; the duration of study was 30 days. Healthy rabbits were taken and hyperlipidaemia was induced by giving high cholesterol diet for four weeks. All animals were divided into th...

Results Dose response anti HBV revealed that methanolic extract C. asiatica indicated that 2.5 mg/mL concentrations was inhibitory to 0.75 pg/mL of HBV. Aqueous and methanolic extract of C. sinensis indicated that 0.5 mg/mL and 0.25 concentrations inhibited HBV, respectively. Interestingly, EGCG indicated 1.5 pg/mL HBV was inhibited by 25μg/mL. These concentrations were well tolerated by HepG2 ...

The objective of this study was to determine antioxidant and cytotoxic efficacies of methanolic and aqueous extracts of Rheum emodi Wall. ex Meissn. rhizome. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical scavenging activities, inhibitory effect on lipid peroxidation and Fe(3+) reducing antioxidant property have been used to investigate antioxidant properties of the extracts. Cytotox...