Context: Mucormycosis is a rare acute opportunistic fungal infection with a high mortality rate. It is commonly seen in immunocompromised individuals. Aims: Oral manifestation of mucormycosis is rare. When it does occur, it commonly affects the palate followed by alveolus. Settings and design: The representative tissue received was 10% formalin fixed, 3 × 3 cm in diameter, and floated on the su...

A 58-year-old man was referred to our institution for an evaluation of nephrotic range proteinuria. Renal biopsy showed a marked expansion of the mesangial matrix and thickening of glomerular basement membrane (GBM) in periodic acid-silver methenamine (PAM). Immunofluorescence (IF) revealed strong staining for the monoclonal kappa light chain. EM demonstrated massive subendothelial and mesangia...

Adverse skin reactions to drugs are frequent, with rates of reaction to many commonly used drugs exceeding 1%. We describe a 29-year-old woman admitted with a history of itching, rash, vesicles on her hands and soles, and edema on her tongue and oropharynx after trimethoprim-sulfamethoxazole, ciprofloxacin, methenamine anhydromethylene citrate, piroxicam, azithromycin, and ceftriaxone intake. E...

The vascular architecture of the developing Sprague-Dawley rat spinal cord from E11 through E16 is reported. The paraffin-embedded cord is serially sectioned in the sagittal, transversal and frontal planes and stained with PAS and methenamine silver. Serial semithin transverse sections are stained with toluidine blue. The results demonstrate two highly integrated vascular systems: one sagittall...

A rare case is presented of a 62-year-old man with primary isolated cryptococcal femoral osteomyelitis. Magnetic resonance imaging (MRI) revealed osteolytic destruction of his left femur. Biopsy was performed firstly. Under microscope, the lesion was compose of numerous large mononuclear cells, scattered multinucleated giant cells, a few lymphocytes and neutrophils, necrosis with serious artifi...

H istologic evaluation of tissues is a quick and easy way to identify fungal organisms, and a strong adjunct to microbiologic culture for diagnosis of fungal infections. Histologic evaluation of granulomatous inflammation and granulomas must include special stains to exclude or include presence of fungi and acid fast bacteria. Gomori Methenamine Silver (GMS) and Periodic acid-Schiff (PAS) are t...

One hundred and twenty determinations of urinary estriol were carried out following acid hydrolysis and gas liquid chromatography. Through the use of a radioactive standard, it was shown that, with an increase in specific gravity (1.001 to 1.025), a steady linear decline of estriol recovery occurred (93% to 56%). The presence of glucose (1-5 gm./100 ml.) gradually diminished estriol recovery (7...

The enterochromaffin cells of the guinea pig duodenum and 5-hydroxytryptamine incorporated into gelatin models gave, after formalin fixation, nearly identical reactions with methenamine silver, ferric-ferricyanide, and diazotized o-aminoazotoluene. Following formaldehyde fixation the indole reaction with p-dimethylaminobenzaldehyde was negative in tissue enterochromaffin cells; similarly the in...

serum proteins of normal adults. Biochem J 1955;61:629–41. 17. Ledue TB, Weiner DL, Sipe J, Poulin SE, Collins MF, Rifai N. Analytical evaluation of particle-enhanced immunonephelometric assays for C-reactive protein, serum amyloid A, and mannose binding protein in human serum. Ann Clin Biochem 1998;35:745–53. 18. Thompson KJ, Shoham S, Connor JR. Iron and neurodegenerative disorders. Brain Res...