Abstract Background Staphylococcus aureus infections are remarkable due to their high morbimortality. In addition, antibiotic resistance of these bacteria is a cause concern since it worsens the patient prognosis and associated higher morbidity, mortality cost treatment. The aim this study was assess clinical performance assay VIASURE Methicillin resistant Real Time Detection Kit in epidemiolog...

Background: Staphylococcus aureus can cause fatal pneumonia. The evolution of bacteria and the overuse antibiotics have enhanced drug resistance methicillin-resistant (MRSA) methicillin-sensitive (MSSA). Objectives: This study aimed to recapitulate microbiological profile clinical characteristics paediatric patients with MRSA. Methods: retrospective was conducted investigate 1372 S. pneumonia f...

ABSTRACT The emergence of livestock-associated methicillin-resistant Staphylococcus aureus strains (LA-MRSA) and the potential role pigs in evolution these has led to increased interest research microorganisms. However, this contributed a lack isolation characterization methicillin-susceptible S. (MSSA). In study, prevalence nursery finishing stages were analyzed. susceptibility profiles antibi...

We report a novel phenotype of methicillin resistance, designated "Eagle-type" resistance, which is characteristic in its resistance to high concentrations of methicillin (64 to 512 microg/ml) and susceptibility to low concentrations of methicillin (2 to 16 microg/ml). The type of resistance was expressed in mutant strains selected with high concentrations (e.g., 128 to 512 microg/ml) of methic...

In the present study, the effectiveness of a rapid and colorimetric nitrate reductase analysis (NRA) method and resazurin microplate assay (REMA) for rapid determination of methicillin resistance among Staphylococcus aureus was investigated. A total of 275 clinical isolates of S. aureus were included in the present study. Among these isolates, 151 had the mecA gene and were resistant to methici...

OBJECTIVE To identify the clinical variables that differentiate MRSA (Methicillin-resistant Staphylococcus aureus) from MSSA (Methicillin-sensitive S. aureus) infection. METHODS Cases having culture isolates of Staphylococcus species were recruited. Baseline and other laboratory parameters were compared between MSSA and MRSA sub-groups to identify the predictors for MRSA. RESULTS Out of 98 ...

Methicillin-resistant Staphylococcus aureus has emerged as a pathogen associated with community-acquired infections worldwide. We report the spectrum of community-acquired S. aureus infections and compare the patients infected with methicillin-susceptible or methicillin-resistant strains among patients aged <20 years. Overall, 90 cases of community-acquired S. aureus were detected in an 11-year...

Methicillin resistance in Staphylococcus aureus Staphylococcus aureus is renowned for countering almost any antibiotic challenge. Its history since the advent of penicillin is one of increasing resistance to antibiotics. Methicillin was the first semisynthetic penicillin resistant to penicillinase to be derived from the penicillin nucleus and was a major advance in the treatment of staphylococc...

Methicillin (intrinsic) resistance of Staphylococcus aureus was suppressed almost completely by regulatory gene (penI(1)) mutations of penicillinase plasmids that made penicillinase production strictly noninducible. Methicillin resistance was restored by secondary regulatory gene mutations that altered the noninducible phenotype or by complementation with a compatible plasmid that did not bear ...

Many methods have been described for the detection of methicillin-resistant Staphylococcus aureus (MRSA), but the heterogeneous expression of methicillin resistance affects the reliability of these methods. The aim of the present study was to evaluate some methods for detecting methicillin resistance in Staphylococcus aureus isolates in a university hospital located in the Northeast of Brazil. ...