First, in the author’s study methylene blue was administered in a dose of 1–2 mg/kg bolus over 10 min and the median time until a maximum hemodynamic response was 2 h after drug administration. Out of 88 patients who received methylene blue, only 39 (44.3%) showed a positive hemodynamic response to the drug. We believe that if the bolus of methylene blue was followed by a continuous infusion of...

In this study, N, Scodoped titania photocatalyst was synthesized through an efficient and straight forward method using a single source, ammonium sulfate, as modification agent of titanium isopropoxide (TTIP) precursor. The catalyst was characterized by X-ray powder diffractometer (XRD), element Analysis of carbon, hydrogen, nitrogen (CHN), scanning electron microscopy (SEM), diffuse reflectanc...

About 10 years ago we discovered that bubbling nitric oxide (NO) gas into KrebsRinger bicarbonate solution containing isolated precontracted strips of bovine coronary artery caused a rapid and pronounced, but transient, relaxant response that was antagonized by oxidized hemoproteins, such as methemoglobin, and by methylene blue. NO activated soluble guanylate cyclase prepared from coronary arte...

About 10 years ago we discovered that bubbling nitric oxide (NO) gas into KrebsRinger bicarbonate solution containing isolated precontracted strips of bovine coronary artery caused a rapid and pronounced, but transient, relaxant response that was antagonized by oxidized hemoproteins, such as methemoglobin, and by methylene blue. NO activated soluble guanylate cyclase prepared from coronary arte...

In the present work, the effect of initial pH of methylene blue solution on the kinetics of dye sorption from synthetic aqueous solution by a natural waste material namely: orange peels, was studied. Kinetic data were measured in batch conditions. Methylene blue uptake was time contact and solution initial pH dependent. Maximum dye sorption was found to occur at initial pH 9. Two simplified kin...

OBJECTIVE To describe photosensitization after prenatal exposure to a toxic amount of methylene blue and to alert pediatricians that, in a review of the literature, photosensitization (which this dye is capable of) has not been reported as a complication of prenatal exposure. DESIGN AND PATIENTS A descriptive report of physical findings and significant laboratory tests in a very low birth wei...

The glass surface modification with 3-(mercaptopropyl) trimethoxysilane (MPTS), gold nano-particles (GN) and guanine rich single strand DNA (ss-DNA) was utilized as a novel and efficient platform for sensing trace concentration of methylene blue (MB) by an inexpensive spectrophotometric method. Methylene Blue (MB) can interact with the guanine base of single strand DNA and absorbed onto glass s...