PURPOSE Photodynamic therapy (PDT) is gaining increasing recognition for breast cancer treatment because it offers local selectivity and reduced toxic side effects compared to radiotherapy and chemotherapy. In PDT, photosensitizer drugs are loaded in different nanomaterials and used in combination with light exposure. However, the most representative issue with PDT is the difficulty of nanomate...

BACKGROUND In vivo stains are the prompt resources, which have emerged in recent years to aid as clinical diagnostic tools in detecting early potentially malignant and malignant lesions. Toluidine blue, by its property of retaining in the increased DNA and RNA cellular activity areas, aids in delineating the suspicious areas. However, it is hazardous if swallowed, and has been shown to have tox...

Aluminium phosphide (AlP) a grain fumigant is the leading cause of intentional poisoning in North India. The mechanisms involved in toxicity are not known and there is no antidote till date. The present study was carried out to investigate the oxygen free radical generation, methemoglobinemia and effect of methylene blue treatment on survival time in rat model of AlP poisoning. AlP (50 mg/kg, i...

A grouping of 138 strains of hemolytic streptococci based on differences in dye-sensitiveness and in final hydrogen-ion concentration of cultures is presented. Three groups are distinguished; (1) human parasitic strains, defined by a final pH range of 5.2 to 5.0 and by failure to reduce methylene blue (1:5000) in milk, (2) bovine strains parasitic in the udder, characterized by a final pH range...

TiO2-coated porous silica glass tubes containing macropores were fabricated and evaluated for their water-purification capacity using aqueous solutions of methylene blue. From the results of photocatalytic degradation tests at different initial methylene blue concentrations, the equilibrium adsorption constant (K) was determined to be 4.6 × 10−2 L μmol−1, and the Langmuir-Hinshelwood rate const...

Vasodilatory shock frequently occurs after cardiac surgery, particularly after cardiac assist device implantation. This complication is often associated with high mortality, especially if refractory to conventional vasoconstrictor treatment. Methylene blue, a guanylate cyclase inhibitor, has been successfully used in the management of vasodilatory shock associated with cardiopulmonary bypass. W...

BACKGROUND Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species. OBJECTIVE To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro. METHOD The experimental design was distributed into four groups (1 - co...

The nano sized TiO2 and ZnO are the most active photocatalysts.  Methylene blue was used as a reference molecule for the photocatalytic degradation. The TiO2 and ZnO can totally remove methylene blue dye. The effect of various process parameters like initial concentration, contact time, dose of catalyst and pH on the extent of removal of dye by photocatalysis in presence o...