background: carum carvi l . (caraway), known as black zeera in iran, has been indicated for the treatment of epilepsy in iranian folk medicine. this study evaluated whether the aqueous extract and essential oil of caraway seeds have anticonvulsant effects in mice. methods: the anticonvulsant effects of the aqueous extract (200, 400, 800, 1600, and 3200 mg/kg, i.p.) and essential oil (25, 50, 10...

objective: as the aqueous extract of capparis spinosa (cs) possess antidiabetic effect, he present study aims to reveal the possible  mechanism of action of cs in diabetic mice.materials and methods: both single and repeated oral administrations of aqueous extract of cs were performed in multi-low dose streptozotocin-induced (mlds) diabetic mice. euglycemic hyperinsulinemic clamp was used in as...

introduction: therapeutic strategies such as chemotherapy can affect gonadal adipose depots. the present study was conducted to assess stereological, morphometric and morphological changes in mouse testicular histoarchitecture structure following bilateral epididymal white adipose tissue lipectomy (biewatx) methods: in this experimental study, adult male mice were divided into three equal group...

the effects of chronic administration of lithium, on acute toxicity of carbamazepine (cbz) in mate albino mice was studied and the ld50 values were determined from dose-probit curves. the results showed that in lithium pretreated animals (animals consumed drinking water contraining 600 mg/l lithium carbonate for 10 days) the ld50 value (the doese corresponding to probit 5) of cbz decreased sign...

objective(s): analgesic effects of oxytocin and it's the other physiological effects were well-known. the aim of present study was determination of nitric oxide role on analgesic effects of oxytocin in mice. materials and methods: 216 male albino mice were divided randomly into two experimental groups, tail flick and formalin test. each experimental group consists of three main groups incl...

administration of apomorphine and amphetamine induces climbing behavior in mice due to stimulation of brain dopamine receptors. in the present study, the effects of adrenoceptor agonists and antagonists on amphetamine-induced climbing have been investigated. intraperitoneal (i.p.) injection of different doses of amphetamine (2,4 and 8 mglkg) induced climbing in mice (p

background: advancement in the treatment of various types of cancer has led to greater patient survival. these treatments essentially have toxic effects on different kinds of cells, such as germ cells. infertility as one of the side effects of cancer treatment has changed the quality of life of young cancer survivors dramatically. melatonin is an antioxidant with receptors in the reproductive s...

conclusions tachyzoite of toxoplasma and dna of this parasite were observed in sub mucosa and muscles of the uterus and in the villis of placenta, but not in histological sections of the fetus. therefore, histological and molecular results were consistent. background toxoplasma gondii is an important zoonotic pathogen. vertical transmission of the parasite occurs when females were infected prim...

introduction: there are general concerns about the hazardous impacts of the cell phones radiation on the human health. in this study, the structural and biochemical changes of the mice kidney were assessed after cell phone exposure in. materials and methods: a total of 40 balb/c mice were randomly divided into the control and experimental groups. the experimental group exposed to cell phone dev...

cyclophosphamide (cp) is one of the anti-neoplastic drugs. despite its numerous clinical applications, it has devastating effects on the testicles and declines the sperm quality in treated patients. this study was aimed to investigate the protective effect of crocin in improving the toxicity induced by cp in reproductive system. in this study, 24 male adult mice (6 to 8 weeks) were randomly div...