background: due to common use of methylphenidate (mph) for the treatment of attention deficit hyperactivity disorder (adhd) and the role of the reproductive system in the production of gametes, studying the effects of this medication on the morphometry of testes, serum testosterone concentration, leydig cells function, and fertility rate was the aim of this study. methods: twenty seven male mic...

diethylstilbestrol (des) was widely used in the past, as the morning after contraception, but its application became extremely limited due to several complications including delayed clear cell adenocarcinoma in female infants. however, the use of des increased during the past decade for hormone replacement therapy. the aim of this study was to investigate possible teratogenicity of this synthet...

citrullus colocynthis (cct) is used in traditional medicine to inhibit the implantation of embryos. the objective of this study was to determine the number of embryos per pregnancy and the mortality rate in pregnant mice. 115 vaginal plug-positive mice were divided into 4 groups. the animals were given 30, 60 and 120 mg/kg hydroalcoholic extract of cct until 17th day of gestation. control group...

side effects of ciprofloxacin (cpfx), a widely used broad spectrum antibiotic with fluoroquinolone core, have been reported in different organs. in the present study we sought to elucidate the impact of ciprofloxacin on sperm chromatin integrity and sperm dna damage using aniline blue and acridine orange technique, respectively. the fertility potential in male mice was also evaluated. nmri male...

parasitic infections of rodents can compromise scientific research as well as the health of the animals and humans. based on previous studies, infection rate of parasitic helminths is different in various regions of iran. the current survey was aimed to determine endoparasitic helminths infection in 138 trapped rodents of kermanshah county, iran. mice and rats were trapped using metal snares fr...

reports indicate that one of the causes of harmful to the genital system, especially the testes stress. stress could be created secondarily after some pathological conditions such as neurological diseases or environmental factors. one of the causes of stress could be scary voices, such as cat voice for mice. in this study we aimed to investigate the testes parameters in the animals that were ex...

recent studies show that synthetic glucocorticoids alter testicular homeostasis, in this regard, the influence of betamethasone as a glucocorticoid widely used on histological changes, epididymal sperm counts and fertility was explored in male mice. the study sample (50 mice) was allocated to 3 treatment groups, placebo and a control group. control group was no injected. only normal saline was ...

some studies suggested that glucocorticoid receptors activities can modulate fear and anxiety. according to that, the purpose of this research is to assess the modulatory effect of glucocorticoid receptors on the anxiety assessed in plus maze. in this research mice with medium weight of 20-25 g were used. the male and female animals separately sorted in two groups as control and experiment rand...

purpose: to evaluate the effects of silver nanoparticles on some serum parameters in mice. materials and methods: forty mice, including twenty male and twenty female, were randomly divided into eight groups: c1 and c2 (male and female control groups, respectively), t1, t2 and t3 (male treatment groups), t4, t5 and t6 (female treatment groups). after the acclimatization period, the treatment gro...

introduction dendritic cells (dcs) are bone marrow-derived cells, which migrate to lymphoid and non-lymphoid organs via blood. liver dcs are believed to play an important role in the regulation of hepatic allograft acceptance. however, because of inherent difficulties in isolating adequate numbers of dcs from liver, limited information is available on the phenotype and functions of liver dcs. t...