Microfluidics allows the manipulation of small quantities of reagents in a high-throughput manner and is therefore highly amenable to single cell characterization and more generally to digital analysis, with applications in fields as varied as genomics, diagnostics, directed evolution, and drug screening. The growing place of microfluidics in biology laboratories encouraged us to develop a ...

We describe a novel demonstration of latex immunoagglutination assay in a paper microfluidics format and subsequent Mie scatter detection using the smart phone’s flash and digital camera as optical sensing platform. The background noise was eliminated through careful optimization of Mie scatter parameters: the diameter of latex beads, surfactant concentration, the angle of scatter detection, et...

We describe droplet microfluidic strategies used to fabricate advanced microparticles that are useful structures for the encapsulation and release of actives; these strategies can be further developed to produce microparticles for advanced drug delivery applications. Microfluidics enables exquisite control in the fabrication of polymer vesicles and thermosensitive microgels from single and high...

This system built from commercially available parts and microfluidics allows for efficient robust readout of HRP/TMB based immunoassays.

Separation and detection are ubiquitous in our daily life they two of the most important steps toward practical biomedical diagnostics industrial applications. A deep understanding working principles examples separation enables a plethora applications from blood test air/water quality monitoring to food safety biosecurity; none which irrelevant public health. Microfluidics can separate detect v...

Microfluidics has risen to a new zone of exploration because its application in numerous fields. The integration microfluidics and sensor technology bridges gaps heat transfer areas, the medical field, chemical industry at microscale flow level. This paper reviews latest work conducted with help microflow parameter measurements microfluidic applications, inventions, novel pathway design, an ass...

A synthetic methodology based on microfluidics has been developed to fabricate monodisperse polymer Janus particles by UV-directed phase separation.

Immiscible aqueous phases, formed by dissolving incompatible solutes in water, have been used in green chemical synthesis, molecular extraction and mimicking of cellular cytoplasm. Recently, a microfluidic approach has been introduced to generate all-aqueous emulsions and jets based on these immiscible aqueous phases; due to their biocompatibility, these all-aqueous structures have shown great ...

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The use of planar fluidic devices for performing small-volume chemistry was first proposed by analytical chemists, who coined the term “miniaturized total chemical analysis systems” ( TAS) for this concept. More recently, the TAS field has begun to encompass other areas of chemistry and biology. To reflect this expanded scope, the broader terms “microfluidics” and “lab-on-a-chip” are now often ...