BACKGROUND Micronutrient deficiencies are common among women in low-income and middle-income countries. Data from randomised trials suggest that maternal multiple micronutrient supplementation decreases the risk of low birthweight and potentially improves other infant health outcomes. However, heterogeneity across studies suggests influence from effect modifiers. We aimed to identify individual...

Knowledge about the impact of maternal food andmicronutrient supplementation on infant micronutrient status is limited. We examined the effect of maternal food and micronutrient supplementation on infant micronutrient status in the Maternal and Infant Nutrition Interventions in Matlab Trial. Pregnant women (n = 4436) were randomized to Early or Usual promotion of enrollment in a food supplement...

Biofortification (increasing the contents of vitamins and minerals through plant breeding or biotechnology) of food crops with micronutrient elements has the potential to combat widespread micronutrient deficiencies in humans. Rice (Oryza sativa L.) feeds more than half of the world's population and is used as a staple food in many parts of Asia. As in other plants, micronutrient transport in r...

OBJECTIVE To examine the immunologic, metabolic, and clinical effects of broad spectrum micronutrient supplementation in HIV-infected patients taking highly active antiretroviral therapy (HAART). DESIGN A prospective, randomized, double-blinded, placebo-controlled trial. METHODS Forty HIV-infected patients taking a stavudine and/or didanosine-based HAART regimen were prospectively randomize...

PURPOSE OF REVIEW To examine current evidence for dietary supplementation with zinc and other micronutrients for primary prevention of multiple micronutrient deficiencies that are known to result from therapies used in the treatment of gastrointestinal inflammatory disorders. RECENT FINDINGS Epidemiological observations and clinical findings have strengthened the concept that both nutritional...

Interventions to address micronutrient deficiencies have large potential to reduce the related disease and economic burden. However, the potential risks of excessive micronutrient intakes are often not well determined. During the Global Summit on Food Fortification, 9-11 September 2015, in Arusha, a symposium was organized on micronutrient risk-benefit assessments. Using case studies on folic a...

Numerous preclinical studies have suggested that micronutrient status is associated with the progression of human immunodeficiency virus (HIV) disease, but results from observational studies are still controversial. The objective was to systematically review the efficacy of multiple micronutrient supplementation on mortality and morbidity in HIV-infected adults. A comprehensive search of the Pu...

patients and methods serum zn and cu level of 43 patients with brucellosis (34 men and 9 women) were compared with 43 matched healthy controls. serum micronutrient concentrations were measured by automatic absorptive spectrophotometry. results mean serum cu concentration was significantly higher in subjects with brucellosis when compared with agematched healthy controls (p<0.05). mean serum zn ...

BACKGROUND Micronutrient deficiencies are a public health concern worldwide negatively affecting maternal and child health outcomes. The primary underlying causes of micronutrient deficiencies are insufficient intake and poor bioavailability of micronutrients. However, reliable data on micronutrient intakes are sparse. The objectives of this study were to identify the key local food sources pro...