Bilateral anophthalmia/microphthalmia represents a rare and severe form of structural eye malformation in different species and has also been observed in cattle (Bähr et al., 2003). Therefore we started to map possible candidate genes for anophthalmia/microphthalmia in cattle. The ceh-10 homeo domain containing homolog (C. elegans) (CHX10) gene is an essential component in the network of genes ...

PURPOSE To investigate the molecular epidemiological basis for the unusually high incidence of sclerocornea, aphakia, and microphthalmia in a village in the Tlaxcala province of central Mexico. METHODS A population census was performed in a village to identify all sclerocornea, aphakia, and microphthalmia cases. Molecular analysis of the previously identified Forkhead box protein E3 (FOXE3) m...