We present a physically rigorous method to calculate solvent-dependent accessible surface areas (ASAs) of amino acid residues in unfolded proteins. ASA values will be larger in a good solvent, where solute-solvent interactions dominate and promote chain extension. Conversely, they will be smaller in a poor solvent, where solute-solute interactions dominate and promote chain collapse. In the met...

PURPOSE The aim of the study is to show, on an MRI scan, that the posterior border of the anterior horn of the lateral meniscus (AHLM) could guide tibial tunnel position in the sagittal plane and provide anatomical graft position. METHOD One hundred MRI scans were analysed with normal cruciate ligaments and no evidence of meniscal injury. We measured the distance between the posterior border ...

The Catmull-Clark subdivision algorithm consists of an operator that can be decomposed into a refinement operator and a successively executed smoothing operator, where the refinement operator splits each face with m vertices into m quadrilateral subfaces and the smoothing operator replaces each internal vertex with an affine combination of its neighboring vertices and itself. Over regular meshe...

Several studies have reported that short sleep duration is a risk factor for obesity and metabolic disease. Moreover, both sleep duration and sleep timing might independently be associated with dietary nutrient intake. In this study, we investigated the associations between self-reported sleep duration and dietary nutrient intake, with and without adjustments for variations in sleep timing (i.e...

An enclosure is a two-sided approximation of a unior multivariate function by a pair of typically simpler functions such that over the domain of interest. Enclosures are optimized by minimizing the width and refined by enlarging the space . This paper develops a framework for efficiently computing enclosures for multivariate polynomials and, in particular, derives piecewise bilinear enclosures ...