There are only few studies on the antibacterial activity of red fruit extract (Pandanus conoideus Lam) against oral pathogenic bacteria. Thus, this study aims to determine effectiveness extracts by looking at Minimum inhibitory Concentrations (MIC) and Minimal Bactericidal (MBC) periodontal The subjects were Streptococcus mutans (ATCC 25175), Fusobacterium nucleatum 25586), Porphyromonas gingiv...

Background. Pseudomonas aeruginosa is a causative agent of nosocomial infections. Chloramphenicol broad-spectrum, inexpensive, and common antibiotic. MexAB-OprM secretory pump that causes the innate resistance this bacterium. This study aimed to evaluate expression MexA gene under treatment copper nanoparticles chloramphenicol. Methods. In study, 49 samples were collected from 11 laboratories i...

A new co-crystal with the formula [Ni(bpy)(acr)2(H2O)]·MA (bpy = 2,2′-bipyridine, acr acrylate and MA melamine) has been synthesized characterized using IR, UV-Vis, thermogravimetric analysis single crystal X-ray diffraction. The complex contains discrete unities of [Ni(bpy)(acr)2(H2O)] melamine linked in a network by both hydrogen bonds π-π stacking interactions. Structural characterization re...

Staphylococcus epidermidis (S. epidermidis) is an opportunistic pathogen with low pathogenicity and a cause of the repeated outbreak of bovine mastitis in veterinary clinical settings. In this report, a biofilm model of S. epidermidis was generated and the minimal inhibitory concentration (MIC) and sub-MIC (SMIC) on bacterial cultures were assessed for the following agents: total alkaloids of S...

Phytomedicines are becoming more popular in treatment of infectious diseases worldwide. Cinnamomum verum essential oil (EO) has been used as a therapeutic alternative for various diseases. This study aimed to evaluate the antibacterial and antibiofilm activity C. leaf EO against Pseudomonas aeruginosa, Staphylococcus aureus Klebsiella pneumoniae. Effect vapor on planktonic cells was determined ...

Multidrug-resistant pathogens have become a major public health concern. There is a great need for the development of novel antibiotics with alternative mechanisms of action for the treatment of life-threatening bacterial infections. Antimicrobial peptides, a major class of antibacterial agents, share amphiphilicity and cationic structural properties with cell-penetrating peptides (CPPs). Herei...

Olive mill wastewater polyphenol extract was tested for antimicrobial activity against 64 strains of Pseudomonas fluorescens responsible for mozzarella discolouration. The extract showed a minimum inhibitory concentration (MIC)50 value of 5 mg/mL and a MIC90 value of 7 mg/mL. The MBC50 and MBC90 values corresponded to 6 and 8 mg/mL, respectively. The MIC concentration (7 mg/mL) was demonstrated...

INTRODUCTION Vancomycin is the cornerstone of therapy against methicillin-resistant Staphylococcus in both community- and hospital-acquired infections. Monitoring vancomycin concentration is essential to prevent over- or underdosing of pediatric patients. However, only initial trough vancomycin concentrations may be needed to optimize dosages. The optimal rate of the trough serum level to the m...

results the minimal inhibitory concentration (mics) values of myrtus communis leaves extract ranged 0.625-5.0 µg/µl and 5-40 µg/µl against tested candida spp. and aspergillus spp., respectively. conclusions results revealed that the ethanolic extract of myrtus communis leaves have antifungal potency against both pathogenic tested fungi, and it can be used as a natural antifungal agent. material...

The virulence and resistance of pathogenic microorganisms are promoted by quorum-sensing (QS) mediated traits biofilms. development antimicrobial agents which can reduce the incidence microbial disrupting establishment biofilms QS, constitute a suitable strategy to emergence strains that resistant antibiotics. In this study, 3-(1,3-dithian-2-ylidene) pentane-2,4-dione ( 1 ) ethyl-2-cyano-2-(1,3...