Molecules that target quorum sensing and biofilm inhibition are useful antimicrobials. In this regard, a new diarylhydrazone was synthesized characterized using infrared, high-resolution mass spectrometry nuclear magnetic resonance experiments as N-[( E)-4-bromo-2,5-diheptyloxybenzylideneamino]-2,4-dinitroaniline (BHBANA). Minimal inhibitory concentrations (MICs) vary from 0.625 to 2.5 mg mL −1...

The purpose of this study was to investigate whether immersion of a denture surface in lemongrass extract (LGE) has effects on C. albicans biofilms, human cell viability and denture surface. Minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) were performed for LGE against C. albicans. For biofilm analysis, discs were fabricated using a denture acrylic resin with s...

A characteristic feature of Staphylococcus aureus is its ability to acquire resistance to antimicrobial agents. There is a need, therefore, for new approaches to combat this pathogen; for example, employing a combination of plant-derived products and antibiotics to overcome bacterial resistance. Indigofera suffruticosa is a plant popularly used to treat infections and has verified antimicrobial...

conclusions antimicrobial and antitoxigenic properties of natural products need a firmly established criterion before they could be offered to application. results a significant reduction in aflatoxin production was noted which was not due to the inhibitory effect but because of antifungal property of the oil. interestingly, the oil promoted toxin production for the reasons yet to be investigat...

The susceptibility of Candida albicans to topical amphotericin B and natamycin was evaluated in a model of stromal keratitis in Dutch-belted rabbits and compared with minimal inhibitory concentrations in vitro. Treatment was delayed 24 hr to allow invasive disease to occur and was then continued for 5 days. Ten strains of Candida albicans comprised the test panel. For amphotericin B, the minima...

Biofilms cause chronic infections that are difficult to treat because of the resistance microorganisms inside them. The goal is assess killing potential cefotaxime against Escherichia coli in biofilms obtained from clinical isolates kept microbiology laboratory Dr. Soetomo Surabaya Hospital. study was conducted by experimental design. Two steps challenged bacterial applying planktonic state and...

The evaluation of the activity of the aqueous and ethyl acetate extracts of the leaves of Piper regnellii was tested against gram-positive and gram-negative bacteria. The aqueous extract displayed a weak activity against Staphylococcus aureus and Bacillus subtilis with minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of 1000 micrograms/ml. The ethyl acetate ex...

background: consumption of mycotoxic foods is associated with several cases of human poisoning, or mycotoxicosis, sometimes resulting in death.   objective: phytopreventive inhibition of aspergillus parasiticus growth and its aflatoxin production by the essential oils extracted from thymus kotschyanus boiss & hohen and zataria multiflora boiss. is reported in this study.   methods: minimal inhi...

<p>One of the local fish resources in South Kalimantan is <em>Anabas testudineus</em> fish. It known that <em>A. mucus has antibacterial activity, but this study only looked at inhibitory mucus. Until now, there been no test for Minimum Inhibitory Concentration (MIC) and Minimal Bactericidal (MBC) testudineus </em>fish One bacteria infect wounds <em>S. aureus...

Sub Minimal Inhibitory concentrations (sub-MIC) of antibiotics, although not able to kill bacteria, can be effect on their physico- chemical characteristics and functions. This study aimed to investigate the effect of sub-MIC of imipenem and piperacillin on the transcriptional expression of virulence related genes algD and lasB in Pseudomonas auroginosa. Five clinical isolates of P. aeruginosa ...