BACKGROUND Significant mitral regurgitation (MR) typically occurs as holosystolic (HS) or mid-late systolic (MLS), with differences in volumetric impact on the left ventricle (LV). We sought to assess outcomes of degenerative MR patients undergoing exercise echocardiography, separated based on MR duration (MLS versus HS). METHODS AND RESULTS We included 609 consecutive patients with ≥III+myxo...

| One of the attractive features of recent metaheuristics is in its robustness and simplicity. To investigate this direction, the single machine scheduling problem is solved by various metaheuristics, such as random multistart local search (MLS), genetic algorithm (GA), simulated annealing (SA) and tabu search (TS), using rather simple inside operators. The results indicate that: (1) simple imp...

The behaviors of the Macrolide-Lincosamide-Streptogramin (MLS) resistance genes were investigated in an anaerobic-aerobic pilot-scale system treating spiramycin (SPM) production wastewater. After screening fifteen typical MLS resistance genes with different mechanisms using conventional PCR, eight detected genes were determined by quantitative PCR, together with three mobile elements. Aerobic s...

There has been an abundance of research within the last couple of decades in the area of multilevel secure (MLS) databases. Recent work in this field deals with the processing of multilevel transactions, expanding the logic of MLS query languages, and utilizing MLS principles within the realm of E-Business. However, there is a basic flaw within the MLS logic, which obstructs the handling of cle...

The microphthalmia with linear skin defects syndrome (MLS) is an X-linked dominant disorder with male lethality. In the majority of the patients reported, the MLS syndrome is caused by segmental monosomy of the Xp22.3 region. To date, five male patients with MLS and 46,XX karyotype ("XX males") have been described. Here we report on the first male case with MLS and an XY complement. The patient...

T cell responses to the product of the minor lymphocyte stimulatory locus Mls-1a involve the selective use of TCR V beta domains (especially V beta 6 and V beta 8.1) and are generally considered to be restricted to the CD4+ mature subset. We show here that CD8+ (presumably MHC class I-restricted) T cells bearing V beta 6 or V beta 8.1 also respond preferentially to Mls-1a determinants either in...

Introduction: The H spectra of certain tumor cells, in vivo tumors and biopsies, show an intense resonance in the 1.26-1.30 ppm area that has been usually assigned to NMR visible mobile lipids (MLs) . The presence of large ML signal seems to correlate with necrotic areas in the tumors 3 and the non-invasive detection of necrosis would suggest a high grade of malignancy in untreated tumors or co...

We consider the problem of static transmissionpower assignment for lifetime maximization of a wireless sensor network with stationary nodes operating in a datagathering scenario. Using a graph-theoretic approach, we propose two distributed algorithms, MLS and BSPAN, that construct spanning trees with minimum maximum (minmax) edge cost. MLS is based on computation of minmaxcost paths from a refe...

In recent years, Lagrangian Coherent Structures (LCS) have been characterized using the Finite-Time Lyapunov Exponent, following the advection of a dense set of particles into a corresponding flow field. The large amount of particles needed to sufficiently map a flow field has been a non-trivial computational burden in the application of LCS. By seeding a minimal amount of particles into the fl...