Objective(s): In this study a series of novel colchicine-like β-acetamidoketones was designed and synthesized as potential tubulin inhibitorsMaterials and Methods: The cytotoxicity of the novel synthesized β-acetamidoketones was assessed against two cancerous cell lines including MCF-7 (human breast cancer cells) and A549 (adenocarcinomi...

Abstract The issue of the effects travel on subjective well-being (SWB) has recently attracted increasing interest in transport studies. A common finding is that affects SWB indirectly through out-of-home activities. However, little known about how to operationalize this relationship. In study, we proposed a conceptual model and estimated structural equation models relating mode use activities ...

A hybrid knee prosthesis is proposed in this letter, which consists of a polycentric structure passive mode for low-torque activities and single-axis active high-torque activities. novel transition mechanism controls self-holding electromagnets switching modes between the four-bar linkage structure. Compared with conventional knee, varying instantaneous center rotation (ICR) can enhance geometr...

seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of rheum palmatem. their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-o-β-d-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). anti-monoamine oxidase (mao) activities of compounds 1–8 were tested. compounds 1 and 8 showe...

the main objective of present paper was to study the validity of agricultural extension indices for ranking iranian provinces in terms of extension and education activities. the study was carried out in two phases. in phase one through review of literature, 137 extension-education indices were identified. the indices were classified in seven fields as following: 1) indices of extension workers,...

This paper presents an overview of substrate integrated waveguide (SIW) design activities at the University of Victoria. Mode-matching techniques (MMTs) are employed to facilitate the design of planar SIW circuits as well as surface mounted waveguide (SMW) components. Active component integration and antenna design employ commercially available field solvers. Each category is highlighted by a s...

In project scheduling, many problems can arise when resource fluctuations are beyond acceptable limits. To overcome this, mathematical techniques have been developed for leveling resources. However, these produce a hard and inflexible approach in scheduling projects. The authors propose a simple resource leveling approach that can be used in scheduling projects with multi-mode execution activit...