BACKGROUND/PURPOSES Monascin (MS) and ankaflavin (AK) produced by Monascus purpureus NTU 568 were proven to show excellent hypolipidemic effects in our previous studies; however, the mechanism is still unclear. METHODS This study used MS, AK, and monacolin K as test substances and performed tests on rats fed high-fat and high-cholesterol diet for 8 weeks. The lipid levels and the related prot...

Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in humans, but still no curative treatment has been developed. Although many explicative theories have been proposed, precise pathophysiological mechanisms are unknown. Due to the importance of astrocytes in brain homeostasis they have become interesting targets for the study of AD. Changes in astrocyte function have...

Hi-Res Print, Annotate, Reference QuickView ACS ActiveView PDF PDF [616K] PDF w/ Links [287K] Full Text HTML Sponsored Access Section: Pharmacology Monascin and Ankaflavin Have More Anti-atherosclerosis Effect and Less Side Effect Involving Increasing Creatinine Phosphokinase Activity than Monacolin K under the Same Dosages Chun-Lin Lee, Yu-Ping Hung, Ya-Wen Hsu, and Tzu-Ming Pan pp 143–150 Pub...