The metabolism of monocarboxylic acids is of central importance for bacteria in their natural habitat as well as during biotechnological production. Although biosynthesis and degradation are well understood, the transport of such compounds is still a matter of discussion. Here we present the identification and characterization of a new transport system in Corynebacterium glutamicum with high af...

Transport of several monocarboxylic acids across the lipid bilayer was examined in liposomes consisting of egg yolk phosphatidylcholine and cholesterol. In the presence of inward proton gradient, salicylic acid (SA) was taken up rapidly by liposomes showing overshoot, saturation and competitive inhibition phenomena. These carrier-mediated like profiles of SA uptake can be explained by assuming ...

The hepatic clearance of mitoxantrone was evaluated in rabbits using both bile-duct cannulated animals and freshly isolated hepatocytes in suspension or in primary culture. Mitoxantrone metabolic behavior was assessed by high-performance liquid chromatography using a method which specifically resolved mitoxantrone from its monoand dicarboxylic acid derivatives. Excretion of mitoxantrone in bile...

This paper presents an up-to-date review of research data on the specific features lactic acid metabolism and its role as effector vital regulatory mechanisms. Lactic is alpha-hydroxy monocarboxylic acid. Physical loads submaximal intensity some diseases can cause dramatic increase content in body fluids. The excessive lactate removed from working muscle either metabolized by other tissues or e...

Aqueous solution, 10 mm, of cyclohexanecarboxylic, cyclohexylacetic, cyclohexylpropionic, cyclohexylbutyric acids (all components of naphthenic acid); cis-1,2-, and trans-1, 4-cyclohexyldicarboxylic acids; 3-cyclohexene-1-carboxylic and cyclohexylsulfamic acids; and cyclohexyl mercaptan were applied to 14-day-old bush bean plants, Phaseolus vulgaris L. cv. Top Crop. Only cyclohexanecarboxylic a...

The effects of secondary metabolites produced by waterlogged soils on net K(+), H(+), and Ca(2+) fluxes were studied in the mature zone of roots of two barley (Hordeum vulgare) cultivars contrasting in their waterlogging (WL) tolerance using the noninvasive microelectrode ion flux measuring technique. In WL-sensitive variety 'Naso Nijo', all three lower monocarboxylic acids (formic, acetic, and...

Since picolinic acid, a tryptophan metabolite yielded by the kynurenine pathway, selectively attenuates quinolinic and kainic acid excitotoxicity that is dependent on the presence of a glutamatergic afferent input, it was hypothesized that this agent may inhibit the presynaptic release of glutamate. Using superfused rat striatal slices, this study examined the potential of picolinic acid, and r...

The residue of no-clean flux (NCF) on the printed circuit board assembly has been one major reasons for corrosion reliability failure electronic devices. source aggressive contamination is carboxylic acid activator as main cleaning agent soldering surfaces. Selecting suitable always concerns due to its conflicting properties, example, suberic a lower boiling point that will help in minimizing r...