Abstract Objective To investigate sleep duration and its associated factors in adolescents aged 11 years from the 2004 Pelotas (Brazil) Birth Cohort Study. Methods Sleep was assessed using a self-report habits. Independent variables included perinatal, sociodemographic, behavioral, health characteristics. The associations were estimated multiple linear regression. Results mean of 3,179 9.3 hour...

It is well known that night sleep is a decisive factor for the effective functioning of the human body and mind. In addition to the role of sleep, older adults report that they are "morning types" and that their cognitive and emotional abilities seem to be at a higher level in the morning hours. In this vein, this study is aimed at examining the effect of sleep combined with the "time of day" c...

UNLABELLED Melatonin has anticarcinogenic properties in experimental models. We undertook a case-cohort study of 928 Icelandic men without prostate cancer (PCa) nested within the Age, Gene/Environment Susceptibility (AGES)-Reykjavik cohort to investigate the prospective association between first morning-void urinary 6-sulfatoxymelatonin (aMT6s) levels and the subsequent risk for PCa, under the ...

QUESTION I received a telephone call from my sister who lives in the United States. She is experiencing moderate symptoms of morning sickness, but she tells me that she was advised to treat her symptoms only pro re nata- meaning, when symptoms re-emerge. Does this make sense? ANSWER No, it does not. Typically, nausea and vomiting of pregnancy continue for weeks and months, and in some cases u...

There is uncertainty about the development of airway tolerance to beta-agonists and the phenomenon of rebound bronchoconstriction on beta-agonist withdrawal. We have recently completed a study of the regular terbutaline and budesonide treatment in asthma. We report our observations on the effect of starting and stopping terbutaline treatment on morning and evening peak flows. The study was a ra...