introduction: several studies indicate that estrogen use increase performance on some tests of cognition especially in postmenopausal women. these steroids have many side effects, thus, other estrogenic agents with fewer side effects are needed to develop alternative treatment strategies. the main objection of this study was to evaluate the effects of different doses of dietary soy meals (with ...

In our first two columns, we described innovative practices that Advanced Practices Council (APC) members shared with their colleagues at recent meetings. In this column, we describe the ideas that Jim Tosone, a long-standing APC member, shared at the October APC meeting. A contributor to the recently published “Complete Idiot’s Guide to the U.S. Constitution,” Tosone explained how understandin...

To examine how hippocampal neurons respond to a mismatch between retrieved and actual experience, we trained rats to find a hidden platform at a particular location in an annular watermaze and then moved the platform. Several cells that were silent at the new platform location before the move fired vigorously when the rat found the goal. The new activity was paralleled by reduced discharge in a...

by KIRSTEN A. MORRIS

1 Roe, C. M., Fagan, A. M., Grant, E. A., Hassenstab, J., Moulder, K. L., Maue, D. D. ..., & Morris, J. C. (2013). Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later. Neurology, 80, 1784-1791. Notes: OBJECTIVES: We compared the ability of molecular biomarkers for Alzheimer disease (AD), including amyloid imaging and CSF biomarkers (Abeta42, tau, ptau181,...