introduction: diseases of the dental pulp and periapical tissues are chiefly caused by microorganisms. antibiotics are used in some endodontic cases; however, successful cases can predominantly be achieved by mechanical and chemical cleaning of the canal or surgical intervention. materials & methods: the aim of this study was to determine the knowledge of general dental practitioners (gdps) in ...

The aim of this study was to investigate the association between the immunohistochemical expression of hypoxia-inducible factor (HIF)-1α and HIF-2α and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters Ktrans and kep in prostate cancer. Therefore, 15 patients with biopsy-confirmed prostate cancer underwent a pre-operative 3T DCE-MRI scan. Immunohistochemical analysis of ...

BACKGROUND MRI is a new and expensive diagnostic technology, which has been used increasingly all over the world. Low back pain is a worldwide prevalent disorder and MRI technique is one of the several ways to diagnose it. This paper aims to identify the appropriateness of lumbar spine MRI prescriptions in Shiraz teaching hospitals using standardized RAND Appropriateness Method (RAM) criteria i...

The purpose of this study was to determine the impact of magnetic resonance imaging (MRI) geometric distortions when using MRI for target delineation and planning for whole-breast, intensity-modulated radiotherapy (IMRT). Residual system distortions and combined systematic and patient-induced distortions are considered. This retrospective study investigated 18 patients who underwent whole-breas...

background: iron-mediated cardiomyopathy is the main complication of thalassemia major (tm) patients. therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. the aim of this study was to evaluate the efficacy of tissue doppler imaging (tdi) to study cardiac iron overload in patients with tm using t2* magnetic resonance (mr) as the gold-standard...

this commentary discusses pertinent issues from hyosun kim’s paper on online prescription drug promotion. the study is well-designed and the findings highlight some of the consequences of the food and drug administration’s (fda’s) decision to deregulate online advertising of prescription drugs. while kim’s findings confirm some of the early concerns, they also provide a perspective of implement...

background: direct thrombin inhibitors and factor xa inhibitors are gaining popularity as alternatives to warfarin for patients requiring anticoagulation. toxicity due to these medications is difficult to manage because overdose experience is very limited and there is no clear guidance on when or whether to use antidote in this setting. case presentation: a 50-year-old man with normal renal fun...

medication errors and adverse drug events can bring about hospitalization, permanent injury, or death. patients due to lack of adequate understanding of instruction may unintentionally misuse a prescribed medicine. the aims of the study were to examine whether patients with low back pain were correctly able to understand physician's instructions regarding drug use and also to identify influenci...

implementation of electronic prescribing system can overcome many problems of the paper prescribing system, and provide numerous opportunities of more effective and advantageous prescribing. successful implementation of such a system requires complete and deep understanding of work content, human force, and workflow of paper prescribing. the current study was designed in order to model the curr...