BACKGROUND AND PURPOSE Perfusion CT (PCT) has the ability to measure quantitative values and produce maps of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). We assessed cerebral hemodynamics by using these parameters and acetazolamide challenge in patients with cerebrovascular steno-occlusive disease. METHODS Fifteen patients underwent PCT with acetazolami...

Conscious awareness of the self as continuous through time is attributed to the human ability to remember the past and to predict the future, a cogitation that has been called "mental time travel" (MTT). MTT allows one to re-experience one's own past by subjectively "locating" the self to a previously experienced place and time, or to pre-experience an event by locating the self into the future...

The tetrazolium salt 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) is used to determine cell viability in assays of cell proliferation and cytotoxicity. MTT is reduced in metabolically active cells to yield an insoluble purple formazan product. However, in this study, using a colorimetric method with MTT, we demonstrated that luteolin and quercetin (both are flavonoids) can...

BACKGROUND AND PURPOSE There are limited indicators available to predict cerebral vasospasm in patients with subarachnoid hemorrhage (SAH). The purpose of this study was to determine if CT perfusion-derived hemodynamic parameters are predictors of vasospasm severity and outcome after experimental SAH. MATERIALS AND METHODS SAH was induced in 25 New Zealand white rabbits. Cerebral blood flow (...