OBJECTİVE: In this study, it was aimed to evaluate the antineoplastic efficacy of Teranecron, which is frequently used in veterinary medicine, on human colorectal adenocarcinoma.
 MATERİALS AND METHODS: Teranecron (TRN) its effectiveness and drug Doxorubicin as a positive control. The cytotoxic activity cell line CaCo-2 investigated. MTT proliferation test determine viability rates. ANOVA ...

OBJECTIVE this study designed to test the antibacterial potency of enrofloxacin (ENR) and essential oils from Zataria multiflora Boiss (ZEO) and Trachyspermum copticum (TEO) on Aeromonas hydrophila. MATERIAL AND METHODS The antibacterial potency of test compounds was determined by several methods including the inhibition zone diameter determination, microbroth dilution method and colorimetric...

Coccoloba mollis (Family Polygonaceae) is a medicinal plant popularly used in cases of memory loss, stress, insomnia, anemia, impaired vision, and sexual impotence, but the scientific literature, to date, lacks studies on the biological effects of this species, particularly with regard to cytotoxicity and induction of DNA damage. The aim of the present study was to assess in vitro (in hepatic H...

Arsenic is a ubiquitous trace element that has been shown to induce both systemic and carcinogenic effects. Epidemiological findings indicate that arsenic is a paradoxical human carcinogen that results in increased risk of skin, lung, bladder, liver and kidney cancers. Although the systemic and carcinogenic effects of arsenic have been widely studied in a variety of systems, the mechanisms of a...

This research is aimed to isolate the active constituents of Ginseng stems and leaves and study their anti-cancer activities. Preparative TLC, spectral data analysis and MTT assay are used to isolate constituents and study anti-cancer activities. Six compounds are isolated from Ginseng stems and leaves, namely 20(S)-ginsenoside Rh1, ginsenoside F3, daucosterol, β-sitosterol, ginsenoside Rd2 and...

BACKGROUND Statin can induce the gene expression of bone morphogenetic protein-2. Red yeast rice (RYR, Hongqu), i.e. rice fermented with Monascus purpureus, contains a natural form of statin. This study demonstrates the effects of RYR extract on bone formation. METHODS Bone defects were created in the parietal bones of two New Zealand white rabbits. In the test animal, two defects were grafte...

objective(s) shark liver oil (slo) is an immunomodulator. macrophages play a key role in host defense against pathogens like fungi. candida albicans have mechanisms to escape immune system. we determined the effect of killed-candida on the in vitro viability of macrophages and the effect of slo on augmentation of this potency. materials and methods peritoneal macrophages were separated and cult...

This study aims to determine the IC50 value of mangrove leaf extract type Rhizophora mucronata Lmk. against viability Hela cells. The samples extracted with three types solvents were previously conducted preliminary research on phytochemical compounds and their toxicity values Meted Brine Shrimp Letality Test (BSLT). In test, highest level was obtained in ethanol a 166.72± 7.72 ppm, then sample...

One major method used to evaluate the biocompatibility of porous tissue engineering scaffolding materials is MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. The MTT cell viability assay is based on the absorbance of the dissolved MTT formazan crystals formed in living cells, which is proportional to the number of viable cells. Due to the strong dye sorption capability ...