Microsatellite instability (MSI) due to defects in DNA mismatch repair genes may be involved in the development of a subset of human ovarian carcinomas. The role of one such gene, hMSH6, in ovarian cancer is not well documented. We investigated the expression of hMSH6 protein in different histotypes of ovarian carcinoma and the associations between loss of hMSH6 protein and tumor grade, disease...

Objectives:The aim of the study is to determine the histopathological features of primary colorectal cancers. Materials and methods: 102 patients with primary colorectal tumors diagnosed over a 5 year period studied histopathologically they were classified using the WHO classification of colorectal malignancies. primary gastrointestinal tumors Diagnosis. Result: Most of the colorectal tumors we...