نتایج جستجو برای: multicomponent reaction
تعداد نتایج: 421340 فیلتر نتایج به سال:
Multicomponent reaction of benzyl halides: Synthesis of [1,2,4]triazolo/benzimidazolo quinazolinones
A multicomponent reaction of triazoloketones, primary amines, and 4-nitrophenyl azide was developed for the synthesis hitherto unknown angularly fused/linear bitriazoles. The two-stage mechanism well proven by isolation intermediate. This sequential consists Cornforth rearrangement triazolization, which has also been demonstrated in a one-pot manner.
Multicomponent Reaction-Based Trimethoprim Analogues as Potential Antibiotics for Resistant Bacteria
Multicomponent reactions (MCRs) represent very interesting tools to reach eco-friendly and sustainable transformations in organic chemistry. In particular, the Biginelli reaction furnishes a easy approach synthesis of library biological active compounds an academic course. Here we describe realization several experiments involving potential inhibitors ?-secretase by reaction. All obtained were ...
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