We describe an extension of the adaptive space-time finite element method (ASTFEM) used in the solution of the Lamm equation to the case of multicomponent reacting systems. We use an operator splitting technique to decouple the sedimentation-diffusion process from the reaction process. The former is solved with an ASTFEM approach based on the Petrov-Galerkin method and on adaptive moving grids,...

Many animals produce and respond to signals made up of multiple components. For example, many avian sexual displays are highly extravagant combinations of visual and acoustic elements, and are described as being 'multicomponent'. One possible reason for the evolution of such complex signals is that they provide more reliable information for receivers. However, receivers also influence signal ev...

Hmim][Tfa] was tested as catalyst for the Biginelli reaction multicomponent reaction under conventional and non conventional heat source i.e. Microwave heating. Low catalyst loading, reduced reaction time and operational simplicity are the main highlights of this proposed protocol. Using our proposed protocol, we tested 30 different biologically active compounds in good yield.

A series of new tetrasubstituted imidazoles 2-phenyl-3-(1, 4, 5-triphenyl-1H-imidazol-2-yl)-1H-indole derivatives substituted with –F, Cl, Br, I,-OCH3 and -NHCOCH3 were synthesized using a multicomponent reaction. The compounds were obtained in good yields by easy workup and with high purity

Egg shell has been utilized as a natural, green, reusable and eco-friendly reagent for the synthesis of spiro[4H-pyran-oxindole] derivatives by one-pot multicomponent reaction of isatins, 1,3-diketones, and malononitrile/ ethyl cyanoacetate. Good functional group tolerance and broad scope of usable substrates are other prominent features of the present methodology.

A new Pd-catalyzed one-pot multicomponent coupling reaction for the construction of benzene ring fused with carbocycle or heterocycle under a Cu-free condition is described.

A novel chemoenzymatic one-pot multicomponent synthesis of thiazole derivatives was developed. A series of thiazole derivatives were synthesized with high yields up to 94% under mild enzyme-catalyzed conditions. The blank and control experiments reveal that trypsin from porcine pancreas (PPT) displayed great catalytic activity to promote this reaction and showed a wide tolerance range towards d...

A practical and green approach for the one-pot multicomponent synthesis of fused tetrazolo[1,5-a]quinazoline derivatives has been described via the condensation of 5- aminotetrazole, dimedone, and various aldehydes using 1-butyl-3-methylimidazolium tetrachloroaluminate [bmim]Cl/AlCl3, as a catalyst and task-specific ionic liquid medium. The catalyst was showed remarkable advantages in compariso...

A series of 2-amino pyridine-3-carbinitrile derivatives incorporated coumarin moiety has developed via multicomponent condensation of 3-acetyl-2H-chromen-2-one, arylaldehydes, malononitrile and ammonium acetate utilizing Brønsted acidic ionic liquid, (4-sulfobutyl)tris(4-sulfophenyl)phosphonium hydrogen sulfate as catalyst under solvent-free conditions. Good yields, short reaction times, straig...