conclusions the result of the current study showed the growing number of nosocomial infections associated with xdr a. baumannii causing difficulties in antibiotic therapy. resistant strains increasingly cause public health problems; therefore, their early detection is essential for healthcare centers. results among the 121 isolated a. baumannii, 44% and 56% were isolated from female and male, r...

conclusion prevalence of p. aeruginosa producing esbl and mdr strains from our clinical samples and environment is still low. results the highest resistance rates from the isolated p. aeruginosa were shown against piperacillin, imipenem, cefotaxime, ceftriaxone, gentamicin, ceftazidime, aztreonam, and ciprofloxacin, respectively. seven isolates (9.2%) were esbl producers. more than 30% of the i...

The quantity of seafood imported and produced by domestic aquaculture farming has increased. Recently, it been reported that multidrug-resistant (MDR) Salmonella Typhimurium may be associated with seafood. However, information is limited to the antimicrobial resistance, virulence properties, genetic diversity S. recovered from This study investigated isolated catfish, shrimp, tilapia. A total 1...

Background: Treatment of chronic sinusitis is complicated due to increase of antibiotic-resistant bacteria. The aim of this study was to determine the multidrug resistance (MDR) pattern of the bacteria causing chronic sinusitis in north of Iran. Methods: This cross-sectional study was carried out on patients with chronic sinusitis. Bacterial susceptibility to antimicrobial agents was determi...

background: treatment of chronic sinusitis is complicated due to increase of antibiotic-resistant bacteria. the aim of this study was to determine the multidrug resistance (mdr) pattern of the bacteria causing chronic sinusitis in north of iran. methods: this cross-sectional study was carried out on patients with chronic sinusitis. bacterial susceptibility to antimicrobial agents was determined...

introduction: infections by multidrug resistant mycobacterium tuberculosis (mdr-tb) is a major public health challenge. secretion of proteins by m. tuberculosis plays an important role in the pathogenesis of the bacterium. we compared the protein profiles of susceptible m. tuberculosis and mdr-tb isolates using proteomic analyses, namely two dimensional gel electrophoresis (2de) and mass spectr...

Drug-resistant tuberculosis is a public health concern. TB that drug-resistant to rifampin and isoniazid known as MDR-TB, whereas XDR-TB MDR-TB also resistant second-line medicines, such fluoroquinolones (levofloxacin, ofloxacin, moxifloxacin). rifampin-resistant (RR-TB), of which 78 percent had multidrug-resistant (MDR-TB) (MDR-TB). Fluoroquinolones are class broad-spectrum antimicrobials have...

conclusions this blis with broad-spectrum activity may be a potential agent for the treatment or control of drug-resistant strains of p. aeruginosa infection. results among the 96 isolates of p. aeruginosa, 2 (2.1%), 94 (97.9%), and 63 (65.6%) were non-mdr, mdr, and xdr, respectively, and 1 (1.1%) was pdr. the most effective antibiotics against these isolates were polymyxins and fosfomycin. a b...

BACKGROUND/AIM Altered redox status has been reported to play a significant role in the development of multidrug resistance (MDR) in leukemia cells. Human biliverdin reductase (hBVR) has been recently identified as a major cytoprotectant; however, its role in MDR has not been yet investigated. In the present study we evaluated the possible role of hBVR in MDR development in the human HL60 leuke...