Background Methods for haplotyping and DNA copynumber typing of single cells are paramount for studying genomic heterogeneity and enabling genetic diagnosis. Before analyzing the DNA of a single cell by microarray or next-generation sequencing, a whole-genome amplification (WGA) process is required, but it substantially distorts the frequency and composition of the cell’s alleles. As a conseque...

in this paper a fuzzy analytical network process model for supporting the vendor selection process in strategic situations is suggested. first, the vendor evaluation problem is putting together by use of the multi-criteria decision-making (mcdm) approach and a five-step hybrid process, which incorporates the technique of fuzzy analytical network process. then the modified topsis (technique for ...

the purpose of this letter is to revisit the nonlinear reaction-diusion modelin porous catalysts when reaction term is fractional function of the concen-tration distribution of the reactant. this model, which originates also in uidand solute transport in soft tissues and microvessels, has been recently givenanalytical solution in terms of taylors series for dierent family of reactionterms. we...

permeability prediction problem has been examined using several methods such as empirical formulas, regression analysis and intelligent systems especially neural networks and fuzzy logic. this study proposes an improved and novel model for predicting permeability from conventional well log data. the methodology is integration of empirical formulas, multiple regression and neuro-fuzzy in a commi...

The purpose of this study is to examine dynamic interdependence between economic development, wealth and income distributions, and discrimination in an integrated Walrasian-general-equilibrium and neoclassical-growth theory. We build a dynamic economy with one consumer goods sector, one capital goods sector, and heterogeneous households. We build a model in which wealth accumulation, income and...

The Ant Colony Optimization method is a heuristic algorithm for solving various optimization problems, particularly the combinatorial optimization problems. Traditional ant-optimization methods might encounter search stagnation owing to a biased pheromone map that is dominated by local optimal trails. To overcome this drawback and lower the number of solution constructions for finding the optim...

A limitation associated with communication-based interventions for problem behavior is the potential for requesting reinforcement at high rates. Multiple-schedule arrangements have been demonstrated to be effective for controlling rates of responding (Hanley, Iwata, & Thompson, 2001). In the current study, we extended previous research by teaching individuals to attend to naturally occurring di...

The present study is to investigate the differences in Ki-67 expression and microvessel density (MVD) among cerebral schistosomiasis, low grade gliomas and high grade gliomas. Expressions of Ki-67 and CD34 in surgical specimens from 12 cases of cerebral schistosomiasis lesions, 12 cases of low grade gliomas and 12 cases of high grade glioma were detected by streptavidin-perosidase immunohistoch...

The aim of this paper is to propose a new multi-sensor target recognition method for solving the problem which the discriminated object has multiple characteristics indexes. The method combines the concept of gray relational analysis (GRA) method and cumulative prospect theory. This method, the characteristic vector matrix was firstly transformed to standardize membership degree decision making...