نتایج جستجو برای: multiple myeloma

تعداد نتایج: 762314  

Journal: :international journal of hematology-oncology and stem cell research 0
mohammad ali mashhadi hematology- oncology department, ali ebne abitaleb hospital, zahedan university of medical sciences, zahedan, iran mehdi hashemi hematology- oncology department, ali ebne abitaleb hospital, zahedan university of medical sciences, zahedan, iran negin khosravi hematology- oncology department, ali ebne abitaleb hospital, zahedan university of medical sciences, zahedan, iran

introduction: the aim of our study is evaluation of response rate of vad (vincristin, adriamycin and dexamethason) regimen as initial treatment in 40 new cases of multiple myeloma. this is the first systemic and classic report of vad regimen in iranian population. methods: all patients with at least stage 2 multiple myeloma or progressive disease after physical examination, para- clinical profi...

This literature review presents the most recent developments in the management of multiple myeloma, which is characterized by the presence of abnormal plasma cells (myeloma cells) that accumulate into the bone marrow. Aspects related to pathophysiology, clinical manifestations, laboratory, study and treatment are described. These pieces of information  are necessary to accomplish a better ...

Multiple myeloma (MM) is a clonal B-lymphocyte neoplasm of terminally differentiated plasma cells. Imaging modalities which allow the recognition of the effects of myeloma cells on the skeletal system have been utilized for a long time. Herein, we represent a patient with generalized osteoporosis and hypercalcemia, who was referred for parathyroid scan, in whom the widespread bone marrow techne...

Journal: :international journal of hematology-oncology and stem cell research 0
farhad shahi department of hematology and medical oncology, cancer research center, cancer institute, imam khomeini hospital complex, tehran university of medical science, tehran, iran marziye ghalamkari internal medicine resident, imam khomeini hospital complex, tehran university of medical science, tehran, iran mehrzad mirzania department of hematology and medical oncology, cancer research center, cancer institute, imam khomeini hospital complex, tehran university of medical science, tehran, iran mahdi khatuni internal medicine resident, imam khomeini hospital complex, tehran university of medical science, tehran, iran

the coexistence of two malignancies is rarely seen. a little association between hematologic malignancies especially multiple myeloma and renal cell carcinoma has been reported in the recent past. several case series revealed a bidirectional association between these two malignancies which may be due to the common risk factors, similar cytokine growth requirements and clinical presentation. her...

M Nazerian

A 79-year-old female came to skin clinic with an ulcer, 15×20 cm, on her left shin. The laboratory report and both the skin and bone marrow biopsies reports, showed pyoderma gangrenosum associated with multiple myeloma. The patient was referred to hematology clinic for treatment. Multiple myeloma has rarely been associated with pyoderma gangrenosum. Multiple myeloma should be investigated...

Journal: :journal of research in medical sciences 0
taleb azarm professor, hematology and oncology center, isfahan university of medical sciences, isfahan, iran mojtaba akbari epidemiologist, school of medicine, isfahan university of medical sciences, isfahan, iran arezoo azarm cellular and molecular biology, isfahan, iran hamid mohager resident, department of internal medicine, school of medicine, isfahan university of medical sciences, isfahan, iran

normal 0 false false false en-us x-none fa background : the aim of the study was to assess the effects of combination of bortezomib moderate dose and continuous oral low dose melphalan and thalidomide and dexamethasone (bmtd regimen) in elderly patients aged ≥ 65 years with relapsed multiple myeloma (mm). methods : twenty four patients with advanced mm were enrolled to receive eight 3-week trea...

Multiple myeloma is a monoclonal malignant proliferation of plasma cells. The disease is more frequent in men, and the average age of patients at the time of diagnosis of the disease is about 60 years. Solitary myeloma may be the first manifestation of the disseminated form of multiple myeloma, which is characterized by multiple skeletal lesions, general metabolic alterations, impairment of ren...

Amirhosein Maali, Hamid Gholipour, Mehdi Azad, Mehrdad Noruzinia, Saeid Abroun, Sasan Ghaffari,

Background: Epigenetic modifications, such as methylation can occur in multiple myeloma. SMG1is an important gene involved in cell growth which defect in methylation of its promoter leads to reduction of cell apoptosis and uncontrolled proliferation. In this study, we identified the methylation status of the SMG1 gene promoter in patients with multiple myeloma. Methods: Methylation status of S...

Journal: :iranian journal of medical sciences 0
maryam amirchaghmaghi atessa pakfetrat pegah mosannen mozafari shadi saghafi

multiple myeloma is a monoclonal malignant proliferation of plasma cells. the disease is more frequent in men, and the average age of patients at the time of diagnosis of the disease is about 60 years. solitary myeloma may be the first manifestation of the disseminated form of multiple myeloma, which is characterized by multiple skeletal lesions, general metabolic alterations, impairment of ren...

Azar Naimi Diana Taheri Faegheh Taghizadeh Noushin Afshar Moghaddam, Shahram Taheri

A 54 year old man with history of cardiomyopathy and chronic fibrillation first presented with bloody diarrhea. Then during the assessment of his abnormal lab. data revealed cast nephropathy in renal biopsy, gamma peak in protein electrophoresis and fine lytic lesions in skull graphy. His bone marrow asp...

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