1. Lysine is readily incorporated into mycobactins P and S. Incorporation is into the hydroxamic acid moieties only and is equal in the mycobactic acid and cobactin portions of the molecule. 2. 2-Amino-6-hydroxyaminohexanoic acid is not taken up by cells of Mycobacterium phlei and is not detectable in extracts of cells actively synthesizing mycobactin. 3. The most abundant material derived from...

The main cause of pulmonary tuberculosis (TB) is infection with Mycobacterium tuberculosis (MTB). We aimed to evaluate the contribution of nontuberculous mycobacteria (NTM) to pulmonary disease in patients from the state of Rondônia using respiratory samples and epidemiological data from TB cases. Mycobacterium isolates were identified using a combination of conventional tests, polymerase chain...

A low-molecular-mass protein from Methylococcus capsulatus (Bath) is responsible for the regulation of formaldehyde dehydrogenase activity in vitro S. Tate and H. Dalton Partial characterization of a major autolysin from Mycobacterium phlei 2. S. Li, T. 1. Beveridge, J. Betts and A. 1. Clarke Oxidation of medium-chain acyl-CoA esters by extracts of Aspergillus niger: enzymology and characteriza...

o-Succinylbenzoate: coenzyme A ligase, an enzyme involved in menaquinone biosynthesis, was purified from Mycobacterium phlei and characterized with respect to isoelectric point, molecular weight, pH optimum, temperature optimum and kinetic data. The enzyme hydrolyses ATP to AMP. The substrate and cofactor specificity of the enzyme was tested with analogues of o-succinylbenzoic acid, different n...

Part 1 issued November 1971 PAGE Effects of Organochlorine Insecticides on Bacterial Growth, Respiration and Viability. By P. W. TRUDGILL, R. WIDDUS and J. S. REES The Effects of Technical Chlordane on Energy Metabolism of Bacillus subtilis. By R. WIDDUS, P. W. TRUDGILL and M. J. MALISZEWSJSI The Effects of Technical Chlordane on Growth and Energy Metabolism of Streptococcus faecalis and Mycoba...

Earlier phases of an investigation concerning the lactic oxidative decarboxylase’ from Mycobacterium phlei (1, 2) extended the initial observations of Edson (3) and Edson and Cousins (4). A similar type of enzyme, obtained from Mycobacterium avium, has been described by Yamamura et al. (5, 6). The flavoprotein character of the enzyme, as well as the absence of associated coenzymes, has been est...