effects of doxycycline on cx43 distribution and cardiac arrhythmia susceptibility of rats after myocardial infarction abstract: this study aimed to observe the effects of doxycycline (dox) on gap junction remodeling after mi and the susceptibility of rats to cardiac arrhythmia. the proximal left anterior descending coronary artery of rats was ligated to establish a myocardial infarction animal ...

background :impact of substance abuse on outcome of hospitalized patients with acute myocardial infarction (mi) is a frequent question. available studies show disagreements over its impact, thus we performed this study to find a clear answer.   methods : in a cross sectional study, 304 patients (include 152 consecutive opium dependents and equal number of independents) with acute mi admitted to...

objective(s) several studies have reported improved response of exercised hearts to myocardial infarction (mi). this study was aimed to evaluate the preventive role of treadmill exercise and diosgenin on cardiac marker enzymes, thiobarbituric acid reactive substances (tbars), total antioxidant status (tas), lipids, and electrocardiographic (ecg) patterns in isoproterenol (iso)-induced myocardia...

background: studies on the prognosis of st elevation myocardial infarction (stemi) versus non-st elevation myocardial infarction (non-stemi) have shown different results. the present study was designed to compare the early outcome and left ventricular systolic function of patients with st and non-st elevation myocardial infarction. methods: the patients' information was derived from 10,065 cons...

determination of pre-hospital delay time of patients with acute myocardial infarction and seeking ways of speeding up the time for reperfusion is an important factor to lower mortality in these patients. this is a cross-sectional study to determine pre-hospital delay time, its components, and related causes and conditions, obtained in 375 patients with prolonged chest pain referred to four hosp...

introduction: myocardial infarction (mi) is associated with increased oxidative stress and reduced antioxidants. some studies have shown that exercise training increases the serum level antioxidants. therefore, this study investigated the effect of rehabilitation training on antioxidant status in patients with myocardial infarction. materials and methods: in this study, 20 patients with myocard...

conclusions we showed that patients with metabolic syndrome have larger infarct size compared to control subjects. background infarct size is an important surrogate end point for early and late mortality after acute myocardial infarction. despite the high prevalence of metabolic syndrome in patients with atherosclerotic diseases, adequate data are still lacking regarding the extent of myocardia...

Introduction: We aimed to assess whether the vasodilator effect of oral dipyridamole on the left ventricular systolic function in patients with suspected CAD is different from that of intravenous (IV) dipyridamole using Tc-99m MIBI myocardial perfusion gated SPECT. Methods: Eighty-nine patients (17 M / 72 W; 61 ± 10 years) were enrolled in this study. The patients underwent a dipyridamole stre...

Serum IgE and beta 2 microglobulin levels were determined in 31 patients suffering from acute myocardial infarction and 30 patients with other forms of ischemic heart disease. The levels of these parameters were studied on the first, third and seventh day after the onset of disease. The immunological method used for the determinations was ELISA Patients with myocardial infarction showed an...

Objective(s): Exercise training is a well-known accelerator for the treatment of chronic heart failure (CHF). The current study aimed to investigate the restorative effects of aerobic interval training (AIT) intervention on myocardial energy metabolism in CHF rats. Materials and Methods: Post-myocardial infarction (MI) heart failure animal model was established. The Sprague-Dawley rats were ran...