AIMS This study was to investigate the expression of microRNA (miR)-144 in malignant solitary pulmonary nodule (SPN) tissues and peripheral blood, as well as the biological function of miR-144 in the occurrence and development of lung cancer. METHODS In this study, 39 malignant and 30 benign SPN patients were included. The expression of miR-144 was examined using quantitative real-time polyme...

The Stochastic Petri Net Package (SPNP) [2] is a versatile modeling tool for solution of Stochastic Petri Net (SPN) models. The SPN models are described in the input language for SPNP called CSPL (C-based SPN Language) which is an extension of the C programming language [8] with additional constructs which facilitate easy description of SPN models. Moreover, if the user does not want to describ...

The solitary pulmonary nodule (SPN) is frequently encountered on chest imaging and poses an important diagnostic challenge to clinicians. The differential diagnosis is broad, ranging from benign granulomata and infectious processes to malignancy. Important concepts in the evaluation of SPNs include the definition, morphologic characteristics via appropriate imaging modalities, and the calculati...

Repair of meiotic double-strand breaks (DSBs) uses the homolog and recombination to yield crossovers while alternative pathways such as nonhomologous end joining (NHEJ) are suppressed. Our results indicate that NHEJ is blocked at two steps of DSB repair during meiotic prophase: first by the activity of the MCM-like protein MEI-218, which is required for crossover formation, and, second, by Rad5...

Source camera identification using the residual noise pattern left by the sensor, or Sensor Pattern Noise, has received much attention by the digital image forensics community in recent years. One notable issue in this regard is that high-frequency components of an image (textures, edges) can be easily mistaken as being part of the SPN itself, due to the procedure used to extract SPN, which is ...

The present work was conducted to isolate and identify different parasites from Indian Major Carp (IMC) Catla catla. During the study period the severity of infection and Parasitic Frequency Index (PFI, %) were also estimated in terms of months, seasons and length groups of fishes. For the investigative purpose different districts of West Bengal were selected considering the potential of fisher...

During a survey of myxosporean parasites of cyprinid fish in Hungary, infections caused by unknown Myxobolus spp. were found in the internal organs of rudd, Scardinius erythrophthalmus, and bleak, Alburnus alburnus. Small plasmodia developed in blood vessels of the kidney, liver, testes and intestinal wall. The parasites were studied on the basis of spore morphology and by histological and mole...

A 61-year-old woman visited our hospital for bilateral multiple lung nodules and a mass in her thorax. She had a long history of multiple metastatic recurrences of solid pseudopapillary neoplasm (SPN); 24 years previously, the patient had undergone pylorus-preserving pancreaticoduodenectomy for a 9.9 × 8.6 cm mass in the pancreatic head. The tumor was diagnosed as an SPN. Nine years later, meta...

We investigated the relationship between action-outcome contingency and stimulus-preceding negativity (SPN), a motivationally sensitive event-related potential. Neuroimaging studies have shown that insular cortex (a known source of the SPN) is more activated prior to rewards that are contingent on prior correct action than rewards that are given gratuitously. We compared two gambling tasks, one...

The radiologic evaluation of the solitary pulmonary nodule (SPN) is a common diagnostic dilemma. Although available clinical data and findings on conventional radiographs are important components in determining the imaging approach to the SPN, evaluation with CT often is necessary for detailed evaluation. This article reviews the radiologist's approach to the evaluation of the SPN, with a parti...