The fabrication of drug nanoparticles (NPs) with process-mediated tunable properties and performances continues to grow rapidly during the last decades. This study investigates the synthesis and phase tuning of nanoparticulate itraconazole (ITR) mesophases using quasi nanoemulsion precipitation from acetone/water systems to seek out an alternative pathway to the nucleation-based NP formation. I...

−Stable hydrocarbon oil (hexadecane, C16)/nonionic surfactant (HCO-60, Span 80)/water system oil-inwater nanoemulsions were prepared by the phase inversion composition method at elevated temperature. To minimize droplet size, the composition ratio for stable nanoemulsions, we experimented by changing the HLB value, oil/surfactant ratio, and droplet volume fraction. When the HLBmix value 11, the...

Introduction: One of the most obvious morphological changes due to aging is the formation of facial wrinkles, which are remarkably visible at middle ages and can have a significant effect on the quality of life of individuals. It is believed that UVB is one of the main causes of aging by stimulating reactive oxygen species. Nanoemulsion was loaded with fullerene, a strong free ...

Objective(s): The application of synthetic antimicrobial and antifungal compounds is reducing in the last decades in the food and nutrition fields owing to their various side effects and increasing interest of consumers to eat natural foodstuffs without artificial constituents. Clove (Syzygium aromaticum) has numerous medicinal properties, including analgesic, antiseptic, stimulants, carminativ...

In this study, a thermosensitive in situ gel nanoemulsion was formulated by low energy method for intranasal delivery of temozolomide to bypass the blood-brain barrier and optimize chemotherapy glioblastoma. Various amounts Labrasol, Transcutol®P, Triacetin were chosen as components based on solubility partial pseudoternary phase diagrams studies. Poloxamer derivatives added selected gelling te...

Abstract Background Microalgae are well-established feedstocks for applications ranging from biofuels to valuable pigments and therapeutic proteins. However, the low biomass productivity using commercially available growth mediums is a roadblock its mass production. This work describes strategy boost algal by an effective CO 2 supplement. Results In present study, novel nanoemulsion-based media...

Garlic oils have promising possibilities for a wide range of applications in the food and pharmaceutical industries. Their widespread utilization is limited as they are lipophilic highly volatile. Furthermore, also possess strong odor low physicochemical stability. Therefore, present study aims to investigate characteristics garlic oil nano-emulsion through investigating its antifungal activity...

Nanotechnology is an enable technology that has the potential to revolutionize agriculture and food systems. Driven by increasing consumer demand for healthy food products, researchers have been applying tools and knowledge in nanotechnology to address the issues relevant to food and nutrition. This concise review is mainly focused on nanoemulsions and polymer micelles-based delivery systems wh...

Given the importance of the extracellular medium during tissue formation, it was wise to develop an artificial structure that mimics the extracellular matrix while having improved physico-chemical properties. That is why the choice was focused on gelatin methacryloyl (GelMA), an inexpensive biocompatible hydrogel. Physicochemical and mechanical properties were improved by the incorporation of n...

Adjuvants enhance immunogenicity of vaccines through either targeted antigen delivery or stimulation of immune receptors. Three cationic nanoparticle formulations were evaluated for their potential as carriers for a DNA vaccine, and muramyl dipeptide (MDP) as immunostimulatory agent, to induce and increase immunogenicity of Mycobacterium tuberculosis antigen encoding plasmid DNA (pDNA). The for...