The construction of functional biomimetic scaffolds that recapitulate the topographical and biochemical features of bone tissue extracellular matrix is now of topical interest in bone tissue engineering. In this study, a novel surface-functionalized electrospun polycaprolactone (PCL) nanofiber scaffold with highly ordered structure was developed to simulate the critical features of native bone ...

Anion exchange polystyrene nanofiber materials (AE) were prepared by electrospinning followed by two-step functionalization of the nanofiber surface by chlorosulfonic acid and ethylendiamine. The photoactive character of these materials was introduced through adsorption of the tetra-anionic 5,10,15,20-tetrakis-(4-sulfonatophenyl)porphyrin photosensitizer (TPPS-AE) on the nanofiber surface or by...

OBJECTIVE The development of combining mesenchymal stem cells (MSCs) with surface modified three-dimensional (3D) biomaterial scaffold provides a desirable alternative for replacement of damaged and diseased tissue. Nanofibrous scaffolds serve as suitable environment for cell attachment and proliferation due to their similarity to the physical dimension of the natural extracellular matrix. In t...

The present work is aimed at investigating the mechanical and in vitro biological properties of polyphenylene ether ether sulfone (PPEES)/nanohydroxyapatite (nHA) composite fibers. Electrospinning was used to prepare nanofiber composite mats of PPEES/nHA with different weight percentages of the inorganic filler, nHA. The fabricated composites were characterized using Fourier transform infrared ...

Although electrospinning is considered a powerful and generic tool for the preparation of nanofiber webs, several issues still need to be overcome for real-world applications. Most of these issues stem from the use of a syringe-based system, where the key factor influencing successful electrospinning is the maintenance of several subtle balances such as those of between the mass and the electri...

Thermal transport in DNA is systematically studied to facilitate the development of DNA-based nanoelectronics in thermal management aspect. Synthesis of crystalline DNAcomposited microfiber and microfilm, DNA nanofiber and DNA nanofiber array are developed in sequence to enable the thermal transport study in them. Thermo-physical properties, including thermal conductivity, thermal diffusivity, ...

in this work, cofe2o4 nanoparticles have been prepared by co-precipitation technique. the synthesized cofe2o4 nanoparticles were applied in the preparation of cofe2o4/polyacrylonitrile fiber nanocomposites by the electrospinning process. the prepared nanoparticles and nanofibers were characterized using the scanning electron microscopy (sem) and x-ray diffraction methods. the results manifested...

in this present study, we examined the differentiation potential of human bone marrow derived mesenchymal stem cells (hbmscs) into hepatocytes on a three-dimentional (3d) nanofibrous scaffold formed by poly (ε-caprolactone) (pcl), collagen and polyethersulfone (pes). the nanofiber was prepared by the electrospining technique. hbmscs were isolated using combining gradient density centrifugation ...

nanofber  mats  of  poly(ε-caprolactone)/nanoclay  nanocomposites  were fabricated by electrospinning. the effects of the solution concentration and  the  nanoclay  content  of  nanocomposite  materials  on  the  fnal nanofber  structure were  investigated. morphology  and  diameter  of  the  nanofbers were studied using optical and scanning electron microscope. it was observed that the  poly(ε...

Electrospinning is regarded as a facile tool to generate biomaterials into a nanofibrous structure. Herein a nanofibrous web constituted of collagen and hydroxyapatite (HA) was produced from their co-precipitated nanocomposite solution by using the electrospinning method. The co-precipitated sol was freeze-dried and the dried product was dissolved in an organic solvent for the electrospinning. ...