Nanoparticles are key components in the advancement of future energy technologies; thus, strategies for preparing nanoparticles in large volume by techniques that are costeffective are required. In the substitution of fossil-fuels by renewable energy resources, nanometersized particles play a key role for synthesizing energy vectors from varying and heterogeneous biomass feedstocks. They are ex...

Multilayer thin films of anionic gold nanoparticles (AuNPs) and cationic phosphorus dendrimers were deposited on 3-(diethoxymethyl-silyl)propylamine (3-APDMES)-coated substrates using layerby-layer (LbL) assembly driven by electrostatic interactions. The growth of Au/dendrimer multilayers composed of AuNPs with diameters of 3 nm and 16 nm and dendrimer with 2 nm diameter was monitored by UV-vis...

The systemic delivery of genetic therapies required for the treatment of inaccessible tumors and metastases remains a challenge despite the development of various viral and synthetic vector systems. Here we show that a synthetic vector system based on polypropylenimine dendrimers has the desired properties of a systemic delivery vehicle and mediates efficient transgene expression in tumors afte...

In molecular biology, polymerase chain reaction (PCR) has played an important role but suffers a general problem of low efficiency and specificity. Development of suitable PCR additives to improve the specificity and efficiency still remains a great challenge. Here we report the use of dendrimer-entrapped gold nanoparticles (Au DENPs) as a novel class of enhancers to improve the specificity and...

Novel highly branched biodegradable macromolecular systems have been developed by grafting carboxymethylchitosan (CMCht) onto low generation poly(amidoamine) (PAMAM) dendrimers. Such structures organize into sphere-like nanoparticles that are proposed to be used as carriers to deliver bioactive molecules aimed at controlling the behavior of stem cells, namely their proliferation and differentia...

One of the primary recent improvements in molecular chemistry is the now decade-old concept of click chemistry. Typically performed as copper-catalyzed azide-alkyne (CuAAC) Huisgen-type 1,3-cycloadditions, this reaction has many applications in biomedicine and materials science. The application of this chemistry in dendrimer synthesis beyond the zeroth generation and in nanoparticle functionali...

A simple method was developed to fabricate Au-Ag nanoparticle/graphene oxide nanocomposites (Au-Ag/GO) by using simultaneous redox reactions between AgNO3, HAuCl4 and GO. The Au-Ag/GO was characterized by x-ray photoelectron spectroscopy, transmission electron microscopy and energy dispersive x-ray spectroscopy. The GO nanosheets acted as the reducing agent and the support for the Au-Ag alloy n...

1. Nanotechnology and Nanomedicine . . . . . . . . . . . . . . . . . . . . 1 2. Medical Nanomaterials and Nanodevices . . . . . . . . . . . . . . . . 3 2.1. Nanopores . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2. Artificial Binding Sites and Molecular Imprinting . . . . . . 4 2.3. Quantum Dots and Nanocrystals . . . . . . . . . . . . . . . . . . 4 2.4. Fullerenes and ...